PCSK5

Gene Symbol PCSK5
Entrez Gene 5125
Alt Symbol PC5, PC6, PC6A, SPC6
Species Human
Gene Type protein-coding
Description proprotein convertase subtilisin/kexin type 5
Other Description prohormone convertase 5|proprotein convertase 6|protease PC6|subtilase|subtilisin/kexin-like protease PC5
Swissprots F5H2G7 Q13527 Q92824 Q96EP4
Accessions AFI24907 CAE75579 CAE75580 EAW62575 EAW62576 EAW62577 Q92824 AI379031 AK023096 AK056202 BAG51646 AK122718 AK225773 AK310862 AL834522 CAD39178 AM393199 CAL38077 BC012064 AAH12064 BM719207 CK023649 CN360310 DA992221 DB491139 DQ892327 ABM83253 DQ895531 ABM86457 DT932737 DV080167 DY655633 HY155058 U49114 AAA91807 U56387 AAC50643 XM_005252039 XP_005252096 XM_011518769 XP_011517071 XM_011518770 XP_011517072 XR_929806 XR_929807 NM_001190482 NP_001177411 NM_006200 NP_006191 NR_120409
Function Likely to represent a widespread endoprotease activity within the constitutive and regulated secretory pathway. Capable of cleavage at the RX(K/R)R consensus motif. Plays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha- integrins. {ECO:0000269|PubMed:19764806, ECO:0000269|PubMed:20555025, ECO:0000269|PubMed:22740495}.
Subcellular Location Isoform PC6A: Secreted. Note=Secreted through the regulated secretory pathway. {ECO:0000250}.
Tissue Specificity Expressed in T-lymphocytes.

PC5/6 CRISPR/Cas9 KO Plasmid (h) - sc-407924 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PC5/6 HDR Plasmid (h) - sc-407924-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PC5/6 Double Nickase Plasmid (h) - sc-407924-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PC5/6 Double Nickase Plasmid (h2) - sc-407924-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PC5/6 CRISPR Activation Plasmid (h) - sc-407924-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PC5/6 CRISPR Activation Plasmid (h2) - sc-407924-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PC5/6 Lentiviral Activation Particles (h) - sc-407924-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PC5/6 Lentiviral Activation Particles (h2) - sc-407924-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PC5/6 siRNA (h) - sc-40886 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PC5/6 shRNA Plasmid (h) - sc-40886-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PC5/6 shRNA (h) Lentiviral Particles - sc-40886-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU032461 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16502 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16502 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PCSK5 siRNA (Human) - CRH3407 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PCSK5 (NM_006200.3) - SHH372028 from Creative biogene

Category siRNA
Species Reactivities Human

PCSK5 shRNA Plasmid (Human) - CHH3407 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PCSK5 miRNA 3'UTR clone - MiUTR3H-03404 from Creative biogene

Species Reactivities Human
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