UACA

Gene Symbol UACA
Entrez Gene 55075
Alt Symbol NUCLING
Species Human
Gene Type protein-coding
Description uveal autoantigen with coiled-coil domains and ankyrin repeats
Other Description nuclear membrane binding protein|uveal autoantigen with coiled coil domains and ankyrin repeats
Swissprots Q9NWC6 Q96NH6 Q9HCL1 Q14DD3 Q9BZF9 Q8N3B8 G3XAG2
Accessions EAW77853 EAW77854 EAW77855 Q9BZF9 AB046781 BAB13387 AF322916 AAG49577 AK000990 BAA91457 AK055435 BAB70922 AK057207 AL834243 CAD38920 AL834464 CAD39123 BC016881 AAH16881 BC113407 AAI13408 BC113409 AAI13410 BC143266 AAI43267 BC143267 AAI43268 BM693348 BU736944 CN303461 XM_005254527 XP_005254584 XM_005254529 XP_005254586 XM_011521752 XP_011520054 XM_011521753 XP_011520055 XM_011521754 XP_011520056 NM_001008224 NP_001008225 NM_018003 NP_060473
Function Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15358194}. Cytoplasm {ECO:0000269|PubMed:15358194}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:15358194}. Note=Expressed diffusely in cytoplasm.
Tissue Specificity Highly expressed in skeletal muscle, heart, kidney and pancreas. Expressed in choroid, retina and epidermal melanocytes. Expressed in eye muscles and thyroid follicular cells. {ECO:0000269|PubMed:11162650, ECO:0000269|PubMed:15358194}.

Nucling (A-4) - sc-514117 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Nucling (A-4): sc-514117. Western blot analysis of Nucling expression in HeLa whole cell lysate.

Nucling (E-12) - sc-135510 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
Nucling (E-12): sc-135510. Western blot analysis of Nucling expression in WI 38 whole cell lysate.

Nucling (N-13) - sc-135511 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
Nucling (N-13): sc-135511. Western blot analysis of Nucling expression in HeLa (A) and MIA PaCa-2 (B) whole cell lysates.

Anti-UACA antibody - ab169684 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-UACA antibody (ab169684) at 1 µg/mlLane 1 : UACA transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-UACA Antibody (aa1075-1125) - LS-C288175 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-UACA Antibody (aa1309-1358) - LS-C145721 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
UACA antibody LS-C145721 Western blot of Fetal Lung lysate. Antibody concentration 1 ug/ml.

Anti-UACA Antibody (aa675-725) - LS-C288173 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human UACA by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-UACA used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.

Anti-UACA Antibody (aa1-50) - LS-C288172 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human UACA by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-UACA used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.

Anti-UACA Antibody (aa675-725) - LS-C286524 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human UACA by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-UACA used at a dilution of 1:250.

UACA Antibody - NBP1-92554 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UACA Antibody - NB100-61622 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UACA Antibody [NB100-61622] - Detection of Human UACA by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-UACA antibody NB100-61622 used for IP at 3 mcg/mg lysate. UACA was also immunoprecipitated by rabbit anti- UACA antibodies NB100-61621 and NB100-61623, which recognize other epitopes.Detection: Chemiluminescence with an exposure time of 3 seconds.

UACA Antibody (AE-5) - NBP2-36443 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone AE-5

UACA Antibody - NB100-61623 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UACA Antibody [NB100-61623] - Detection of Human UACAon HeLa whole cell lysate using NB100-61623. UACA was also immunoprecipitated by rabbit anti-UACA antibodies NB100-61621 and NB100-61622.

UACA Antibody - H00055075-B03P from Novus Biologicals

Prices $349.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

UACA Antibody (AE-5) [Azide Free] - NBP2-36444 from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone AE-5

UACA Antibody (AE-5) [Alexa Fluor (R) 647] - NBP2-36444AF647 from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone AE-5

UACA Antibody (AE-5) [Alexa Fluor (R) 488] - NBP2-36444AF488 from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone AE-5

UACA Antibody (AE-5) [Alexa Fluor (R) 405] - NBP2-36444AF405 from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone AE-5

UACA Antibody (AE-5) [DyLight 650] - NBP2-36444C from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone AE-5

UACA Antibody (AE-5) [Biotin] - NBP2-36444B from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone AE-5

UACA Antibody (AE-5) [Allophycocyanin] - NBP2-36444APC from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone AE-5

UACA Antibody (AE-5) [Alexa Fluor (R) 700] - NBP2-36444AF700 from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone AE-5

UACA Antibody (AE-5) [DyLight 405] - NBP2-36444V from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone AE-5

UACA Antibody (AE-5) [DyLight 350] - NBP2-36444UV from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone AE-5

UACA Antibody (AE-5) [DyLight 550] - NBP2-36444R from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone AE-5
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