UACA

Gene Symbol	UACA
Entrez Gene	55075
Alt Symbol	NUCLING
Species	Human
Gene Type	protein-coding
Description	uveal autoantigen with coiled-coil domains and ankyrin repeats
Other Description	nuclear membrane binding protein|uveal autoantigen with coiled coil domains and ankyrin repeats
Swissprots	Q9NWC6 Q96NH6 Q9HCL1 Q14DD3 Q9BZF9 Q8N3B8 G3XAG2
Accessions	EAW77853 EAW77854 EAW77855 Q9BZF9 AB046781 BAB13387 AF322916 AAG49577 AK000990 BAA91457 AK055435 BAB70922 AK057207 AL834243 CAD38920 AL834464 CAD39123 BC016881 AAH16881 BC113407 AAI13408 BC113409 AAI13410 BC143266 AAI43267 BC143267 AAI43268 BM693348 BU736944 CN303461 XM_005254527 XP_005254584 XM_005254529 XP_005254586 XM_011521752 XP_011520054 XM_011521753 XP_011520055 XM_011521754 XP_011520056 NM_001008224 NP_001008225 NM_018003 NP_060473
Function	Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:15358194}. Cytoplasm {ECO:0000269|PubMed:15358194}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:15358194}. Note=Expressed diffusely in cytoplasm.
Tissue Specificity	Highly expressed in skeletal muscle, heart, kidney and pancreas. Expressed in choroid, retina and epidermal melanocytes. Expressed in eye muscles and thyroid follicular cells. {ECO:0000269|PubMed:11162650, ECO:0000269|PubMed:15358194}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human UACA ELISA Kit (Sandwich ELISA) - LS-F8945 from LifeSpan Bioscience Category ELISA Kit Prices $790.00 Sizes 1 plate Sensitivity 0.108 ng/ml Range 0.313-20 ng/ml

Human UACA ELISA Kit (Sandwich ELISA) - LS-F12889 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.78 Range 0.313-20 ng/ml

Anti-UACA antibody (IgG), Human, ELISA Kit - CSB-E14908h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA), Human, ELISA Kit - SEL897Hu from ARP American Research Products Category ELISA Kit Prices $790.00 Sizes 96 t Sensitivity 0.312-20ng/mL Range 0.312-20ng/mL

Uveal autoantigen with coiled-coil domains and ankyrin repeats, UACA, Human, ELISA Kit - E3054h from ARP American Research Products Category ELISA Kit Prices $660.00 Sizes 96 t Range 0.78-50 ng/mL

Uveal Autoantigen With Coiled Coil Domains and Ankyrin Repeats, ELISA Kit - MBS061704 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Uveal Autoantigen With Coiled Coil Domains and Ankyrin Repeats, ELISA Kit - MBS059664 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Uveal Autoantigen With Coiled Coil Domains and Ankyrin Repeats, ELISA Kit - MBS108604 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Uveal Autoantigen With Coiled Coil Domains and Ankyrin Repeats, ELISA Kit - MBS080277 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Uveal Autoantigen With Coiled Coil Domains and Ankyrin Repeats, ELISA Kit - MBS058774 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Uveal Autoantigen With Coiled Coil Domains and Ankyrin Repeats, ELISA Kit - MBS061871 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Uveal Autoantigen With Coiled Coil Domains and Ankyrin Repeats, ELISA Kit - MBS087246 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA), ELISA Kit - MBS2019652 from MyBioSource Category ELISA Kit Prices $410.00, $610.00, $830.00, $3,420.00, $6,200.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.108ng/mL. Range 0.313-20ng/mL

uveal autoantigen with coiled-coil domains and ankyrin repeats, ELISA Kit - MBS9323802 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anti Uveal autoantigen with coiled coil domains and ankyrin repeats Antibodies, ELISA Kit - MBS745688 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Anti Uveal autoantigen with coiled-coil domains and ankyrin repeats Antibodies, ELISA Kit - MBS754476 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anti Uveal autoantigen with coiled-coil domains and ankyrin repeats Antibodies, ELISA Kit - MBS748335 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anti Uveal autoantigen with coiled-coil domains and ankyrin repeats Antibodies, ELISA Kit - MBS746807 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Anti Uveal autoantigen with coiled-coil domains and ankyrin repeats Antibodies, ELISA Kit - MBS746573 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Anti Uveal autoantigen with coiled-coil domains and ankyrin repeats Antibodies, ELISA Kit - MBS753787 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Anti Uveal autoantigen with coiled-coil domains and ankyrin repeats Antibodies, ELISA Kit - MBS748964 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anti Uveal autoantigen with coiled-coil domains and ankyrin repeats Antibodies, ELISA Kit - MBS749482 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anti Uveal autoantigen with coiled-coil domains and ankyrin repeats Antibodies, ELISA Kit - MBS753335 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Anti Uveal autoantigen with coiled-coil domains and ankyrin repeats Antibodies, ELISA Kit - MBS748482 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anti Uveal autoantigen with coiled-coil domains and ankyrin repeats Antibodies, ELISA Kit - MBS749283 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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