BRMS1

Gene Symbol	BRMS1
Entrez Gene	25855
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	breast cancer metastasis suppressor 1
Other Description	breast cancer metastasis-suppressor 1
Swissprots	Q6IAI2 Q9HCU9
Accessions	AAK69131 EAW74513 EAW74514 EAW74515 EAW74516 Q9HCU9 AF147350 AF159141 AAG00075 AI797564 AK310991 AK313773 BAG36511 AL050008 CAB43235 BC009834 AAH09834 BM312965 BU734281 CB130346 CB529276 CR457173 CAG33454 NM_001024957 NP_001020128 NM_015399 NP_056214 NM_001024958
Function	Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down- regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma. {ECO:0000269|PubMed:14581478, ECO:0000269|PubMed:17000776, ECO:0000269|PubMed:20830743}.
Subcellular Location	Nucleus. Cytoplasm. Note=Predominantly nuclear.
Tissue Specificity	Expression levels are higher in term placentas than in early placentas. Low levels of expression observed in normal pregnancies and in molar pregnancies. {ECO:0000269|PubMed:12414911}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BRMS1 full length protein - ab153248 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human BRMS1 full length protein - ab177609 from Abcam Category Protein Prices $301.00 Sizes 20 µg Source E. coli Species Human

BRMS1 Antibody Blocking Peptide - LS-E6603 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BRMS1 Antibody Blocking Peptide - LS-E23331 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BRMS1 Recombinant Protein - H00025855-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

BRMS1-AntibodyN-term-Blocking-peptide - BP19387a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant human Breast cancer metastasis-suppressor 1 (OPCA00555) - OPCA00555 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human BRMS1 protein - orb245216 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

BRMS1 protein (His tag) - 80R-3635 from Fitzgerald Category Protein Prices $275.00 Sizes 20 µg Source E.coli

BRMS1 Blocking Peptide - abx063795 from Abbexa Category Peptide Species Human, Bovine, Monkey

BRMS1 Blocking Peptide - abx063794 from Abbexa Category Peptide Species Human, Mouse, Rat, Monkey

BRMS1 (1-246, T7 tag) - AR51322PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 100 µg Source E. coli Species Human

BRMS1 (1-246, T7 tag) - AR51322PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 20 µg Source E. coli Species Human

BRMS1 - H00025855-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

BRMS1 - H00025855-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

BRMS1, 1-246aa, Human, T7 tag, E.coli - 01-P2502 from ARP American Research Products Category Protein Prices $139.00, $369.00, $849.00 Sizes 5 µg, 20 µg, 100 µg Species Human

BRMS1 fusion protein - ag8939 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

BRMS1 fusion protein - Ag9104 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human BRMS1, GST-tagged - BRMS1-10293H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human BRMS1, T7-tagged - BRMS1-5006H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human breast cancer metastasis suppressor 1, T7 tagged - BRMS1-405H from Creative Biomart Category Protein Source E.coli Species Human

BRMS1 Blocking Peptide - CBP2600 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Monkey

BRMS1 Blocking Peptide - CBP2601 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Bovine, Monkey

BRMS-1 (E43) Peptide - BS2144P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant human Breast cancer metastasis-suppressor 1 - CSB-EP048144h CSB-BP048144h CSB-MP048144h from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

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