BRMS1

Gene Symbol BRMS1
Entrez Gene 25855
Alt Symbol -
Species Human
Gene Type protein-coding
Description breast cancer metastasis suppressor 1
Other Description breast cancer metastasis-suppressor 1
Swissprots Q6IAI2 Q9HCU9
Accessions AAK69131 EAW74513 EAW74514 EAW74515 EAW74516 Q9HCU9 AF147350 AF159141 AAG00075 AI797564 AK310991 AK313773 BAG36511 AL050008 CAB43235 BC009834 AAH09834 BM312965 BU734281 CB130346 CB529276 CR457173 CAG33454 NM_001024957 NP_001020128 NM_015399 NP_056214 NM_001024958
Function Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down- regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma. {ECO:0000269|PubMed:14581478, ECO:0000269|PubMed:17000776, ECO:0000269|PubMed:20830743}.
Subcellular Location Nucleus. Cytoplasm. Note=Predominantly nuclear.
Tissue Specificity Expression levels are higher in term placentas than in early placentas. Low levels of expression observed in normal pregnancies and in molar pregnancies. {ECO:0000269|PubMed:12414911}.

BRMS1 CRISPR/Cas9 KO Plasmid (h) - sc-403753 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRMS1 HDR Plasmid (h) - sc-403753-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRMS1 Double Nickase Plasmid (h) - sc-403753-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRMS1 Double Nickase Plasmid (h2) - sc-403753-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRMS1 CRISPR Activation Plasmid (h) - sc-403753-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRMS1 CRISPR Activation Plasmid (h2) - sc-403753-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRMS1 Lentiviral Activation Particles (h) - sc-403753-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRMS1 Lentiviral Activation Particles (h2) - sc-403753-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRMS1 siRNA (h) - sc-60290 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BRMS1 shRNA Plasmid (h) - sc-60290-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BRMS1 shRNA (h) Lentiviral Particles - sc-60290-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BRMS1 RNAi - H00025855-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU004591 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4064 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

BRMS1 siRNA (Human) - CRH8547 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BRMS1 RNAi - H00025855-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

BRMS1 - MBS8202433 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human BRMS1 (NM_015399.3) - SHH247766 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human BRMS1(NM_015399.3) - SHG105217 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human BRMS1(NM_001024957.1) - SHG105271 from Creative biogene

Category siRNA
Species Reactivities Human

BRMS1 shRNA Plasmid (Human) - CHH8547 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

BRMS1 miRNA 3'UTR clone - MiUTR1H-00946 from Creative biogene

Species Reactivities Human

BRMS1 miRNA 3'UTR clone - MiUTR1H-00947 from Creative biogene

Species Reactivities Human
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