Gene Symbol | ADAMTS13 |
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Entrez Gene | 11093 |
Alt Symbol | ADAM-TS13, ADAMTS-13, C9orf8, VWFCP, vWF-CP |
Species | Human |
Gene Type | protein-coding |
Description | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
Other Description | A disintegrin and metalloproteinase with thrombospondin motifs 13|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13|vWF-cleaving protease|von Willebrand factor-cleaving protease |
Swissprots | Q9UGQ1 Q96L37 Q710F6 Q9H0G3 Q711T8 Q6UY16 Q76LX8 |
Accessions | AAS54901 AAS54902 AAS54903 AAS54904 ABD72606 ADD92168 CAI12850 CAI12851 CAI12852 EAW88083 EAW88084 EAW88085 EAW88086 EAW88087 EAW88088 Q76LX8 AB069698 BAB69487 AF414400 AAL11094 AF414401 AAL11095 AJ011374 CAB66157 AJ305314 CAC83682 AJ420810 CAD12729 AJ420811 CAD12730 AK124983 BAG54119 AK292439 BAF85128 AL136809 CAB66743 AV655072 AW197188 AY055376 AAL17652 AY358118 AAQ88485 BC034404 BC039251 BC103828 BC103829 BC103830 BC172369 AAI72369 DB069518 XM_011518174 XP_011516476 XM_011518175 XP_011516477 XM_011518176 XP_011516478 XM_011518177 XP_011516479 XM_011518178 XP_011516480 XM_011518179 XP_011516481 XM_011518180 XP_011516482 XM_011548750 XP_011547052 XM_011548751 XP_011547053 XM_011548752 XP_011547054 XM_011548753 XP_011547055 XM_011548754 XP_011547056 XM_011548755 XP_011547057 XM_011548756 XP_011547058 NM_139025 NP_620594 NM_139026 NP_620595 NM_139027 NP_620596 NR_024514 NM_139028 |
Function | Cleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation. {ECO:0000269|PubMed:19880749}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:12791682}. Note=Secretion enhanced by O-fucosylation of TSP type-1 repeats. |
Tissue Specificity | Plasma. Expressed primarily in liver. {ECO:0000269|PubMed:11574066}. |
ADAMTS-13 (C-17) - sc-21511 from Santa Cruz Biotechnology
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ADAMTS-13 (F-16) - sc-21510 from Santa Cruz Biotechnology
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ADAMTS-13 (H-300) - sc-25584 from Santa Cruz Biotechnology
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Anti-ADAMTS13 antibody - ab28274 from Abcam
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Anti-ADAMTS13 antibody - ab71550 from Abcam
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Anti-ADAMTS13 antibody - ab28273 from Abcam
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Anti-ADAMTS13 antibody - ab72335 from Abcam
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Anti-ADAMTS13 antibody - ab28275 from Abcam
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Anti-ADAMTS13 antibody - ab60930 from Abcam
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Anti-ADAMTS13 antibody - ab72075 from Abcam
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Anti-ADAMTS13 antibody [20A5] - ab90786 from Abcam
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Anti-ADAMTS13 antibody [EPR6132] - ab177940 from Abcam
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Anti-ADAMTS13 Antibody (aa825-875, Agarose) - LS-C291142 from LifeSpan Bioscience
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Anti-ADAMTS13 Antibody (aa75-125, Agarose) - LS-C291136 from LifeSpan Bioscience
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Anti-ADAMTS13 Antibody (aa250-350, Agarose) - LS-C291121 from LifeSpan Bioscience
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Anti-ADAMTS13 Antibody (aa150-200, Agarose) - LS-C291139 from LifeSpan Bioscience
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Anti-ADAMTS13 Antibody (C-Terminus, Agarose) - LS-C291143 from LifeSpan Bioscience
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Anti-ADAMTS13 Antibody (aa1328-1428) - LS-C306097 from LifeSpan Bioscience
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Anti-ADAMTS13 Antibody (aa75-125) - LS-C287830 from LifeSpan Bioscience
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Anti-ADAMTS13 Antibody (aa250-350) IHC-plus⢠- LS-B11288 from LifeSpan Bioscience
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Anti-ADAMTS13 Antibody (aa34-688) - LS-C124985 from LifeSpan Bioscience
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Anti-ADAMTS13 Antibody (aa34-688) - LS-C124984 from LifeSpan Bioscience
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Anti-ADAMTS13 Antibody (C-Terminus) - LS-C126610 from LifeSpan Bioscience
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Anti-ADAMTS13 Antibody (aa34-688, Biotin) - LS-C124986 from LifeSpan Bioscience
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Anti-ADAMTS13 Antibody (C-Terminus) - LS-C126611 from LifeSpan Bioscience
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