FKBP8

Gene Symbol	FKBP8
Entrez Gene	23770
Alt Symbol	FKBP38, FKBPr38
Species	Human
Gene Type	protein-coding
Description	FK506 binding protein 8, 38kDa
Other Description	38 kDa FK506-binding protein|38 kDa FKBP|FK506-binding protein 8 (38kD)|FKBP-38|FKBP-8|PPIase FKBP8|hFKBP38|peptidyl-prolyl cis-trans isomerase FKBP8|rotamase
Swissprots	Q53GU3 C8C9T5 Q7Z349 Q86YK6 Q14318
Accessions	AAC28753 EAW84709 EAW84710 EAW84711 Q14318 AK026952 AK300571 BAH13306 AK313363 BAG36163 AL042208 AL555689 AM392905 CAL37783 AY225339 AAO39020 AY278607 AAQ84561 BC009966 AAH09966 BM719161 BM790404 BQ953871 BU752982 BX538124 CAD98028 BX647405 BX647720 DB471984 DQ893085 ABM84011 DQ896353 ABM87352 GQ372970 ACU65096 XM_011527862 XP_011526164 XM_011527863 XP_011526165 XM_011527864 XP_011526166 NM_001308373 NP_001295302 NM_012181 NP_036313
Function	Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis. {ECO:0000269|PubMed:12510191, ECO:0000269|PubMed:15757646, ECO:0000269|PubMed:16176796}.
Subcellular Location	Isoform 1: Mitochondrion membrane; Single- pass membrane protein; Cytoplasmic side.
Tissue Specificity	Widely expressed. Highest levels seen in the brain. Highly abundant in the retina. {ECO:0000269|PubMed:18385096}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FKBP38 peptide - ab51928 from Abcam Category Peptide Prices $290.00 Sizes 50 µg

Human FKBP38 peptide - ab99883 from Abcam Category Peptide

Human FKBP38 protein fragment - ab93970 from Abcam Category Protein Source E. coli Species Human

FKBP38 / FKBP8 Antibody Blocking Peptide - LS-E8070 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FKBP38 / FKBP8 Antibody Blocking Peptide - LS-E17047 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FKBP38 / FKBP8 Antibody Blocking Peptide - LS-E17048 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FKBP38 / FKBP8 Antibody Blocking Peptide - LS-E26729 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human FKBP38 Protein - H00023770-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

FKBP8-Antibody-Center-Blocking-peptide - BP5990c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

FKBP8 blocking peptide - GTX88728-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

FKBP38 Blocking Peptide - 33R-10864 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

FKBP8 Blocking Peptide - 33R-3478 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FKBP8 Blocking Peptide - 33R-1277 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human FKBP8 Protein - abx066675 from Abbexa Category Protein Source E.coli Species Human

FKBP38 Peptide - AC21-1567-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

FKBP8 / FKBP38 - H00023770-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

FKBP8 / FKBP38 - H00023770-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

FKBP8 / FKBP38 control peptide - AP00313CP-N from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

FK506 Binding Protein 8 (FKBP8), Human - 20-8962 from ARP American Research Products Category Protein Prices $609.00 Sizes 50 µg Source E.coli Species Human

FKBP8 Peptide - 46-841P from ProSci Category Peptide

FKBP8 fusion protein - ag1649 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant FK506 Binding Protein 8 (FKBP8) - RPE678Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant FK506 Binding Protein 8 (FKBP8) - RPE678Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant FK506 Binding Protein 8 (FKBP8) - RPE678Hu01 from Cloud-clone Category Protein Source E.coli Species Human

FKBP38 Blocking Peptide - 3666BP-50 from Biovision Category Peptide Prices $95.00 Sizes 50 µg

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