RALBP1

Gene Symbol RALBP1
Entrez Gene 10928
Alt Symbol RIP1, RLIP1, RLIP76
Species Human
Gene Type protein-coding
Description ralA binding protein 1
Other Description 76 kDa Ral-interacting protein|DNP-SG ATPase|dinitrophenyl S-glutathione ATPase|ral-interacting protein 1|ralA-binding protein 1
Swissprots D3DUI0 Q15311
Accessions EAX01601 EAX01602 EAX01603 EAX01604 EAX01605 Q15311 AB209924 BAD93161 AK300845 BAG62496 AY517554 AAT44527 BC013126 AAH13126 BF794440 BQ224100 BQ674032 BX352266 DQ891604 ABM82530 EU176588 ABW03389 L42542 AAB00103 NM_006788 NP_006779
Function Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin. {ECO:0000269|PubMed:11437348, ECO:0000269|PubMed:12775724, ECO:0000269|PubMed:7673236}.
Subcellular Location Membrane {ECO:0000269|PubMed:11437348}; Peripheral membrane protein {ECO:0000269|PubMed:11437348}.
Tissue Specificity Expressed ubiquitously but at low levels. Shows a strong expression in the erythrocytes. {ECO:0000269|PubMed:11437348}.
Top Pathways Pancreatic cancer

Human-RALBP1-cDNA-Clone - DC03568 from Abgent, a WuXi AppTec company

Prices $884.25
Sizes 10 µg
Species Human
Accession BC013126

RALBP1 cDNA (ANA11515) - ANA11515 from Aviva Systems Biology

Prices $189.00
Sizes 1 µg
Accession BC013126

RALBP1 cDNA (ANA11516) - ANA11516 from Aviva Systems Biology

Prices $189.00
Sizes 1 µg
Accession BC013126

RALBP1 cDNA (ANA11517) - ANA11517 from Aviva Systems Biology

Prices $189.00
Sizes 1 µg
Accession BC013126

RALBP1 - MBS1274632 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC013126

Human RALBP1 cDNA clone(NM_006788.3) - CDFH015859 from Creative Biomart

Species Human
Accession NM_006788.3

Human RALBP1 ORF clone(NM_006788.3) - CDCL185936 from Creative Biomart

Species Human
Accession NM_006788.3

Human RALBP1 ORF Clone(NM_006788.3) - CDCL173228 from Creative Biomart

Species Human
Accession NM_006788.3

Human RALBP1 ORF Clone(NM_006788.3) - CDCR293701 from Creative Biomart

Species Human
Accession NM_006788.3

Human RALBP1 ORF Clone(NM_006788.3) - CDCR293702 from Creative Biomart

Species Human
Accession NM_006788.3

Human RALBP1 ORF Clone(NM_006788.3) - CDCR293703 from Creative Biomart

Species Human
Accession NM_006788.3

Human RALBP1 ORF clone(NM_006788.3) - CDCL185936 from Creative biogene

Species Human
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