RALBP1

Gene Symbol RALBP1
Entrez Gene 10928
Alt Symbol RIP1, RLIP1, RLIP76
Species Human
Gene Type protein-coding
Description ralA binding protein 1
Other Description 76 kDa Ral-interacting protein|DNP-SG ATPase|dinitrophenyl S-glutathione ATPase|ral-interacting protein 1|ralA-binding protein 1
Swissprots D3DUI0 Q15311
Accessions EAX01601 EAX01602 EAX01603 EAX01604 EAX01605 Q15311 AB209924 BAD93161 AK300845 BAG62496 AY517554 AAT44527 BC013126 AAH13126 BF794440 BQ224100 BQ674032 BX352266 DQ891604 ABM82530 EU176588 ABW03389 L42542 AAB00103 NM_006788 NP_006779
Function Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin. {ECO:0000269|PubMed:11437348, ECO:0000269|PubMed:12775724, ECO:0000269|PubMed:7673236}.
Subcellular Location Membrane {ECO:0000269|PubMed:11437348}; Peripheral membrane protein {ECO:0000269|PubMed:11437348}.
Tissue Specificity Expressed ubiquitously but at low levels. Shows a strong expression in the erythrocytes. {ECO:0000269|PubMed:11437348}.
Top Pathways Pancreatic cancer

Ral BP-1 CRISPR/Cas9 KO Plasmid (h) - sc-402752 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ral BP-1 HDR Plasmid (h) - sc-402752-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ral BP-1 Double Nickase Plasmid (h) - sc-402752-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ral BP-1 Double Nickase Plasmid (h2) - sc-402752-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ral BP-1 CRISPR Activation Plasmid (h) - sc-402752-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ral BP-1 CRISPR Activation Plasmid (h2) - sc-402752-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ral BP-1 Lentiviral Activation Particles (h) - sc-402752-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ral BP-1 Lentiviral Activation Particles (h2) - sc-402752-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ral BP-1 siRNA (h) - sc-36376 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ral BP-1 shRNA Plasmid (h) - sc-36376-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ral BP-1 shRNA (h) Lentiviral Particles - sc-36376-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU012421 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17923 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17923 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11266 from Sigma-Aldrich

Category miRNA

RALBP1 siRNA (Human) - CRH7454 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RALBP1 - MBS8235227 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human RALBP1(NM_006788.3) - SHR163068 from Creative biogene

Category siRNA
Species Reactivities Human

Ral BP-1 CRISPR/Cas9 KO Plasmid (h2) - sc-402752-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ral BP-1 HDR Plasmid (h2) - sc-402752-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RALBP1 shRNA Plasmid (Human) - CHH7454 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

RALBP1 miRNA 3'UTR clone - MiUTR1H-08610 from Creative biogene

Species Reactivities Human
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