MAGI2

Gene Symbol	MAGI2
Entrez Gene	9863
Alt Symbol	ACVRIP1, AIP-1, AIP1, ARIP1, MAGI-2, SSCAM
Species	Human
Gene Type	protein-coding
Description	membrane associated guanylate kinase, WW and PDZ domain containing 2
Other Description	activin receptor interacting protein 1|atrophin-1-interacting protein 1|atrophin-1-interacting protein A|membrane-associated guanylate kinase inverted 2|membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2
Swissprots	A7E2C3 Q9NP44 A4D1C1 Q86UL8 O60510 Q9UDU1 Q86UI7 O60434 Q9UDQ5
Accessions	AAC23438 AAC25530 AAC61488 AAC79151 AAD15413 AAF66080 AAP21886 AAP22360 EAL24194 EAW77021 EAW77022 EAW77023 EAW77024 EAW77025 Q86UL8 AA448362 AA890379 AB014605 BAA31680 AF038563 AAC05370 AK297353 BAH12560 AK297580 BAH12619 AK298988 BAH12916 AK308685 AK309012 BC150277 AAI50278 Z19922 XM_011516718 XP_011515020 XM_011516719 XP_011515021 XM_011516720 XP_011515022 XM_011516721 XP_011515023 XM_011516722 XP_011515024 XM_011516723 XP_011515025 XM_011516724 XP_011515026 XM_011516725 XP_011515027 XM_011516726 XP_011515028 XM_011516727 XP_011515029 XM_011516728 XP_011515030 XM_011516729 XP_011515031 NM_001301128 NP_001288057 NM_012301 NP_036433
Function	Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. {ECO:0000269|PubMed:10760291}.
Subcellular Location	Cytoplasm {ECO:0000250}. Late endosome {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Localized diffusely in the cytoplasm before nerve growth factor (NGF) stimulation. Recruted to late endosomes after NGF stimulation. Membrane-associated in synaptosomes (By similarity). {ECO:0000250}.
Tissue Specificity	Specifically expressed in brain. {ECO:0000269|PubMed:9647693}.
Top Pathways	Tight junction, TNF signaling pathway, Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MAGI-2 (C-17) - sc-11529 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

MAGI-2 (D-15) - sc-11528 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

MAGI-2 (H-60) - sc-25664 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

MAGI-2 (N-19) - sc-11526 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

MAGI-2 (V-15) - sc-11527 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-AIP1 antibody - ab97343 from Abcam Prices $304.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

Anti-AIP1 antibody - ab137255 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-AIP1 antibody - ab5946 from Abcam Prices $242.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-MAGI2 / AIP-1 Antibody (aa1443-1455) - LS-C54467 from LifeSpan Bioscience Prices $335.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-MAGI2 / AIP-1 Antibody (aa206-255) - LS-C292156 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-MAGI2 / AIP-1 Antibody (aa233-282) - LS-C145398 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-MAGI2 / AIP-1 Antibody (Glu255) - LS-C177170 from LifeSpan Bioscience Prices $345.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-MAGI2 / AIP-1 Antibody (clone 6F5) - LS-C139290 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 6F5

Anti-MAGI2 / AIP-1 Antibody (aa221-270) - LS-C119124 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-MAGI2 / AIP-1 Antibody (aa1393-1455) - LS-C185650 from LifeSpan Bioscience Prices $335.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

MAGI2 Antibody - AF7117 from Novus Biologicals Prices $99.00, $359.00 Sizes 25 µg, 100 µg Host Goat Clonality Polyclonal

MAGI2 Antibody - NBP1-89261 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

MAGI2 Antibody - NBP1-31015 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

MAGI2 Antibody - H00009863-A01 from Novus Biologicals Prices $269.00 Sizes 50 µl Host Mouse Clonality Polyclonal

MAGI2 Antibody (6C8) - H00009863-M01 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 6C8

MAGI2 Antibody (6F5) - H00009863-M02 from Novus Biologicals Prices $349.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 6F5

Monoclonal Anti-MAGI2 antibody produced in mouse - SAB1404762 from Sigma-Aldrich Prices $347.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 6F5

Anti-MAGI2 antibody produced in rabbit - SAB4503718 from Sigma-Aldrich Prices $335.50 Sizes 100 µg Host Rabbit Clonality Polyclonal

Monoclonal Anti-MAGI2 antibody produced in mouse - WH0009863M1 from Sigma-Aldrich Prices $347.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 6C8

Anti-MAGI2 antibody produced in rabbit - HPA013650 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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