Bbc3

Gene Symbol Bbc3
Entrez Gene 170770
Alt Symbol PUMA, PUMA/JFY1
Species Mouse
Gene Type protein-coding
Description BCL2 binding component 3
Other Description BH3-only|Bcl-2 binding component 3|bcl-2-binding component 3|p53 up-regulated modulator of apoptosis
Swissprots Q99ML1
Accessions EDL42101 Q99ML1 AF332560 AAK31317 BC044782 AAH44782 BC060370 AAH60370 BC147261 AAI47262 BC147262 AAI47263 XM_006539575 XP_006539638 XM_006539577 XP_006539640 XM_006539578 XP_006539641 XM_006539579 XP_006539642 XM_006539580 XP_006539643 XM_006539581 XP_006539644 XM_006539582 XP_006539645 XM_006539583 XP_006539646 XM_006539584 XP_006539647 NM_133234 NP_573497
Function Essential mediator of p53/TP53-dependent and p53/TP53- independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53 (By similarity). Regulates ER stress-induced neuronal apoptosis. {ECO:0000250, ECO:0000269|PubMed:21159964, ECO:0000269|PubMed:22761832}.
Subcellular Location Mitochondrion. Note=Localized to the mitochondria in order to induce cytochrome c release. {ECO:0000250}.
Top Pathways p53 signaling pathway, Huntington's disease, Measles, Hippo signaling pathway

Recombinant Mouse Bcl-2-binding component 3(Bbc3) - CSB-YP859563MO CSB-EP859563MO CSB-BP859563MO CSB-MP859563MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Bcl-2-binding component 3 (Bbc3), Recombinant Protein - MBS1294760 from MyBioSource

Category Protein
Prices $940.00, $940.00, $1,165.00, $1,165.00, $1,400.00, $1,400.00, $1,865.00, $1,865.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse
Search more