AZI2

Gene Symbol	AZI2
Entrez Gene	64343
Alt Symbol	AZ2, NAP1, TILP
Species	Human
Gene Type	protein-coding
Description	5-azacytidine induced 2
Other Description	5-azacytidine induced gene 2|5-azacytidine-induced protein 2|NAK-associated protein 1|NF-kappa-B-activating kinase-associated protein 1
Swissprots	C9JB40 A8K3M2 Q9H6S1 Q9BQF1 H7BXU6 Q86W99
Accessions	AAF22368 AAF22369 CAJ42721 EAW64392 EAW64393 EAW64394 EAW64395 EAW64396 EAW64397 EAW64398 Q9H6S1 AK025592 BAB15182 AK290637 BAF83326 AY151386 AAO05967 BC001139 BC001853 BG777644 BM546093 BM982133 BX327318 BX386357 BX648471 CB995808 CF528511 DA485515 XM_005265392 XP_005265449 XM_005265393 XP_005265450 XM_011534009 XP_011532311 XM_011534010 XP_011532312 XM_011534011 XP_011532313 NM_001134432 NP_001127904 NM_001134433 NP_001127905 NM_001271650 NP_001258579 NM_022461 NP_071906
Function	Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine- protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1. {ECO:0000269|PubMed:14560022, ECO:0000269|PubMed:15611223, ECO:0000269|PubMed:21931631}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:14560022}.
Tissue Specificity	Widely expressed. Abundant expression seen in the pancreas and testis. {ECO:0000269|PubMed:14560022}.
Top Pathways	RIG-I-like receptor signaling pathway

• Antibodies
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human AZI2 full length protein - ab163822 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

AZI2 / NAP1 - H00064343-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

AZI2 / NAP1 - H00064343-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

AZI2 fusion protein - Ag6892 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

AZI2 fusion protein - ag6755 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

NAP1 Blocking Peptide - CBP2755 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Monkey

Recombinant Human 5-azacytidine-induced protein 2(AZI2) - CSB-YP863992HU CSB-EP863992HU CSB-BP863992HU CSB-MP863992HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

AZI2 / NAP1 (transcript variant 1) - TP311435 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

5-azacytidine-induced protein 2 (AZI2), Recombinant Protein - MBS1329977 from MyBioSource Category Protein Prices $1,160.00, $1,160.00, $1,395.00, $1,395.00, $1,860.00, $1,860.00, $2,325.00, $2,325.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

AZI2 peptide - orb218618 from Biorbyt Category Peptide

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