AZI2

Gene Symbol AZI2
Entrez Gene 64343
Alt Symbol AZ2, NAP1, TILP
Species Human
Gene Type protein-coding
Description 5-azacytidine induced 2
Other Description 5-azacytidine induced gene 2|5-azacytidine-induced protein 2|NAK-associated protein 1|NF-kappa-B-activating kinase-associated protein 1
Swissprots C9JB40 A8K3M2 Q9H6S1 Q9BQF1 H7BXU6 Q86W99
Accessions AAF22368 AAF22369 CAJ42721 EAW64392 EAW64393 EAW64394 EAW64395 EAW64396 EAW64397 EAW64398 Q9H6S1 AK025592 BAB15182 AK290637 BAF83326 AY151386 AAO05967 BC001139 BC001853 BG777644 BM546093 BM982133 BX327318 BX386357 BX648471 CB995808 CF528511 DA485515 XM_005265392 XP_005265449 XM_005265393 XP_005265450 XM_011534009 XP_011532311 XM_011534010 XP_011532312 XM_011534011 XP_011532313 NM_001134432 NP_001127904 NM_001134433 NP_001127905 NM_001271650 NP_001258579 NM_022461 NP_071906
Function Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine- protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1. {ECO:0000269|PubMed:14560022, ECO:0000269|PubMed:15611223, ECO:0000269|PubMed:21931631}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:14560022}.
Tissue Specificity Widely expressed. Abundant expression seen in the pancreas and testis. {ECO:0000269|PubMed:14560022}.
Top Pathways RIG-I-like receptor signaling pathway

NAP1 CRISPR/Cas9 KO Plasmid (h) - sc-413003 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAP1 HDR Plasmid (h) - sc-413003-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAP1 Double Nickase Plasmid (h) - sc-413003-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAP1 Double Nickase Plasmid (h2) - sc-413003-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAP1 CRISPR Activation Plasmid (h) - sc-413003-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAP1 CRISPR Activation Plasmid (h2) - sc-413003-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAP1 Lentiviral Activation Particles (h) - sc-413003-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAP1 Lentiviral Activation Particles (h2) - sc-413003-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAP1 siRNA (h) - sc-78308 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NAP1 shRNA Plasmid (h) - sc-78308-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NAP1 shRNA (h) Lentiviral Particles - sc-78308-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU090951 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3790 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3790 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

AZI2 siRNA (Human) - CRJ1991 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AZI2 - MBS8210256 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AZI2 shRNA Plasmid (Human) - CHJ1991 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AZI2 miRNA 3'UTR clone - MiUTR3H-10889 from Creative biogene

Species Reactivities Human

AZI2 miRNA 3'UTR clone - MiUTR3H-10890 from Creative biogene

Species Reactivities Human

AZI2 miRNA 3'UTR clone - MiUTR3H-10891 from Creative biogene

Species Reactivities Human
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