AZI2

Gene Symbol AZI2
Entrez Gene 64343
Alt Symbol AZ2, NAP1, TILP
Species Human
Gene Type protein-coding
Description 5-azacytidine induced 2
Other Description 5-azacytidine induced gene 2|5-azacytidine-induced protein 2|NAK-associated protein 1|NF-kappa-B-activating kinase-associated protein 1
Swissprots C9JB40 A8K3M2 Q9H6S1 Q9BQF1 H7BXU6 Q86W99
Accessions AAF22368 AAF22369 CAJ42721 EAW64392 EAW64393 EAW64394 EAW64395 EAW64396 EAW64397 EAW64398 Q9H6S1 AK025592 BAB15182 AK290637 BAF83326 AY151386 AAO05967 BC001139 BC001853 BG777644 BM546093 BM982133 BX327318 BX386357 BX648471 CB995808 CF528511 DA485515 XM_005265392 XP_005265449 XM_005265393 XP_005265450 XM_011534009 XP_011532311 XM_011534010 XP_011532312 XM_011534011 XP_011532313 NM_001134432 NP_001127904 NM_001134433 NP_001127905 NM_001271650 NP_001258579 NM_022461 NP_071906
Function Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine- protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1. {ECO:0000269|PubMed:14560022, ECO:0000269|PubMed:15611223, ECO:0000269|PubMed:21931631}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:14560022}.
Tissue Specificity Widely expressed. Abundant expression seen in the pancreas and testis. {ECO:0000269|PubMed:14560022}.
Top Pathways RIG-I-like receptor signaling pathway

Anti-AZI2 antibody - ab65242 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of AZI2 staining in Human normal stomach formalin fixed paraffin embedded tissue section, performed on a Leica Bond™ system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab65242, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-AZI2 antibody - ab123024 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-AZI2 antibody (ab123024) at 1 µg/ml + THP1 cell lysate at 10 µg

Anti-AZI2 antibody - ab125523 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-AZI2 antibody (ab125523) at 1 µg/ml + 721_B cell lysate at 10 µgSecondaryGoat anti-Rabbit IgG-HRP

Anti-AZI2 antibody [EPR14698] - C-terminal - ab192253 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14698
Anti-AZI2 antibody [EPR14698] - C-terminal (ab192253) at 1/5000 dilution + HeLa cell lysate at 20 µgSecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-AZI2 / NAP1 Antibody (aa196-204) - LS-C148034 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-AZI2 / NAP1 Antibody (aa10-59) - LS-C119267 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HepG2 cells, using AZI2 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-AZI2 / NAP1 Antibody (aa69-118) - LS-C146157 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
AZI2 / NAP1 antibody LS-C146157 Western blot of 1 Cell lysate. Antibody concentration 1 ug/ml.

Anti-AZI2 / NAP1 Antibody (C-Terminus) - LS-C345770 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of AZI2 Antibody with human 786-0 Whole Cell lysate.

Anti-AZI2 / NAP1 Antibody (aa170-219) - LS-C146158 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
AZI2 / NAP1 antibody LS-C146158 Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.

Anti-AZI2, N-Terminal antibody produced in rabbit - SAB4502753 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-AZI2, C-Terminal: <B>Cat. No. SAB4502753</B>: Immunoblotting analysis of extracts from HepG2 cells, using Anti-AZI2, C-Terminal antibody. The lane on the left was treated with the Anti-AZI2, C-Terminal antibody. The lane on the right (negative control) was treated with both Anti-AZI2, C-Terminal antibody and the synthesized immunogen peptide.

Anti-AZI2 antibody produced in rabbit - HPA035258 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-AZI2: <B>Cat. No. HPA035258</B>: Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in parietal cells.

AZI2 antibody - N-terminal region (ARP62738_P050) - ARP62738_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

AZI2 antibody - middle region (ARP62739_P050) - ARP62739_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

AZI2 Antibody - C-terminal region (ARP74410_P050) - ARP74410_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NAP1-Antibody - AP51007 from Abgent, a WuXi AppTec company

Prices $295.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-NAP1 Antibody at 1:1000 dilution + HepG2 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 45 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

AZI2 antibody - GTX87461 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-AZI2 antibody used in Western blot. GTX87461

AZI2 Antibody (OAAF02678) - OAAF02678 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Nap1 antibody - STJ94343 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

AZI2/NAP1 antibody - 15042-1-AP from Proteintech Group

Prices $279.00
Sizes con: 61 μg/150μl
Host Rabbit
Clonality Polyclonal
HepG2 cells were subjected to SDS PAGE followed by western blot with 15042-1-AP( AZI2 Antibody) at dilution of 1:1000

AZI2 Polyclonal Antibody - PA000866-C11698 from Syd Labs

Prices $150.00, $250.00
Sizes 50 µg, 100 µg

AZI2 Antibody - 34065 from Signalway Antibody

Prices $189.00, $279.00
Sizes 50 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HepG2 cells, using AZI2 antibody #34065.

AZI2 Antibody - E11-11698C from Enogene

Prices $225.00
Sizes 100 μg
Host Rabbit

AZI2 Antibody - C11698 from Assay Biotechnology

Prices $175.00, $275.00
Sizes 50 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysates from HepG2 cells, using AZI2 Antibody. The lane on the right is blocked with the synthesized peptide.

Human AZI2 Antibody - GWB-ASD882 from Genway Biotech

Prices $180.00, $300.00
Sizes 50 μg, 100 μg
Host Rabbit
Clonality Polyclonal

AZI2 Antibody - GWB-MW664G from Genway Biotech

Prices $404.00
Sizes 50 µg
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