Gene Symbol | ASGR1 |
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Entrez Gene | 432 |
Alt Symbol | ASGPR, ASGPR1, CLEC4H1, HL-1 |
Species | Human |
Gene Type | protein-coding |
Description | asialoglycoprotein receptor 1 |
Other Description | C-type lectin domain family 4 member H1|hepatic lectin H1 |
Swissprots | I3L1X1 P07306 |
Accessions | EAW90256 EAW90257 EAW90258 P07306 AB070933 BAB83508 AK124286 AK308375 AK308677 BC032130 AAH32130 BM818592 BQ653541 BT019873 AAV38676 CR542052 CAG46849 DQ892030 ABM82956 DQ895221 ABM86147 FJ410292 ACQ90237 M10058 AAA51785 XM_011523860 XP_011522162 XM_011523861 XP_011522163 NM_001197216 NP_001184145 NM_001671 NP_001662 |
Function | Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. |
Subcellular Location | Isoform H1a: Membrane; Single-pass type II membrane protein. |
Tissue Specificity | Expressed exclusively in hepatic parenchymal cells. |
Top Pathways | Thyroid hormone synthesis |
Human Asialoglycoprotein Receptor 1 full length protein - ab132495 from Abcam
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Human Asialoglycoprotein Receptor 1 peptide - ab98248 from Abcam
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Human Asialoglycoprotein Receptor 1 protein fragment - ab151893 from Abcam
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ASGR1 / ASGPR Antibody Blocking Peptide - LS-E3935 from LifeSpan Bioscience
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ASGR1 / ASGPR Antibody Blocking Peptide - LS-E11958 from LifeSpan Bioscience
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ASGPR1 Recombinant Protein - H00000432-P01 from Novus Biologicals
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ASGR1-Antibody-N-term-Blocking-Peptide - BP16133a from Abgent, a WuXi AppTec company
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Recombinant Human ASGPR1, CF - 4394-AS-050 from R&D Systems
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Human ASGR1 protein - orb245682 from Biorbyt
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Human ASGPR1 protein (His Tag) - orb138214 from Biorbyt
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Human ASGPR1 protein - orb49209 from Biorbyt
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ASGR1 Blocking Peptide - 33R-8004 from Fitzgerald
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ASGR1 - H00000432-P01-10 from Acris Antibodies
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ASGR1 - H00000432-P01-25 from Acris Antibodies
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Asialoglycoprotein Receptor 1, ASGPR1, Human, Recombinant - 19-C428 from ARP American Research Products
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ASGR1 fusion protein - Ag2310 from Proteintech Group
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Recombinant Human ASGPR1 Protein - BP001226-C428 from Syd Labs
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Recombinant Human ASGR1, His-tagged - ASGR1-26517TH from Creative Biomart
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Recombinant Human ASGR1, His-tagged - ASGR1-586H from Creative Biomart
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Recombinant Human ASGR1, GST-tagged - ASGR1-587H from Creative Biomart
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Recombinant Human ASGR1, GST-tagged - ASGR1-588H from Creative Biomart
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Recombinant Human ASGR1, His-tagged - ASGR1-589H from Creative Biomart
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Recombinant Asialoglycoprotein Receptor 1 (ASGR1) - RPB189Hu01 from Uscn Life Science Inc.
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Recombinant Asialoglycoprotein Receptor 1 (ASGR1) - RPB189Mu01 from Uscn Life Science Inc.
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Human ASGPR1 / ASGR1 Protein (His Tag) - 10773-H07H-50 from Sino Biological
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