Gene Symbol | ASGR1 |
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Entrez Gene | 432 |
Alt Symbol | ASGPR, ASGPR1, CLEC4H1, HL-1 |
Species | Human |
Gene Type | protein-coding |
Description | asialoglycoprotein receptor 1 |
Other Description | C-type lectin domain family 4 member H1|hepatic lectin H1 |
Swissprots | I3L1X1 P07306 |
Accessions | EAW90256 EAW90257 EAW90258 P07306 AB070933 BAB83508 AK124286 AK308375 AK308677 BC032130 AAH32130 BM818592 BQ653541 BT019873 AAV38676 CR542052 CAG46849 DQ892030 ABM82956 DQ895221 ABM86147 FJ410292 ACQ90237 M10058 AAA51785 XM_011523860 XP_011522162 XM_011523861 XP_011522163 NM_001197216 NP_001184145 NM_001671 NP_001662 |
Function | Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. |
Subcellular Location | Isoform H1a: Membrane; Single-pass type II membrane protein. |
Tissue Specificity | Expressed exclusively in hepatic parenchymal cells. |
Top Pathways | Thyroid hormone synthesis |
ASGPR1 (A-5) - sc-393849 from Santa Cruz Biotechnology
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ASGPR1 (N-18) - sc-13467 from Santa Cruz Biotechnology
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ASGPR1 (8D7) - sc-52623 from Santa Cruz Biotechnology
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ASGPR1/2 (E-1) - sc-166633 from Santa Cruz Biotechnology
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ASGPR1/2 (FL-291) - sc-28977 from Santa Cruz Biotechnology
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Anti-Asialoglycoprotein Receptor 1 antibody - ab42488 from Abcam
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Anti-Asialoglycoprotein Receptor 1 antibody - ab88042 from Abcam
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Anti-Asialoglycoprotein Receptor 1 antibody - ab127896 from Abcam
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Anti-Asialoglycoprotein Receptor 1 antibody - ab169977 from Abcam
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Anti-Asialoglycoprotein Receptor 1 antibody - ab123792 from Abcam
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Anti-ASGR1 / ASGPR Antibody (clone 8D7) - LS-C140169 from LifeSpan Bioscience
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Anti-ASGR1 / ASGPR Antibody (clone 8D7, FITC) - LS-C140170 from LifeSpan Bioscience
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Anti-ASGR1 / ASGPR Antibody (aa100-149) - LS-C30414 from LifeSpan Bioscience
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Anti-ASGR1 / ASGPR Antibody (aa1-30, AP) - LS-C251862 from LifeSpan Bioscience
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Anti-ASGR1 / ASGPR Antibody (clone 8D7) - LS-C204173 from LifeSpan Bioscience
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Anti-ASGR1 / ASGPR Antibody (aa1-30, APC) - LS-C251863 from LifeSpan Bioscience
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Anti-ASGR1 / ASGPR Antibody (aa1-30, FITC) - LS-C251865 from LifeSpan Bioscience
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Anti-ASGR1 / ASGPR Antibody (aa1-30, PE) - LS-C251867 from LifeSpan Bioscience
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Anti-ASGR1 / ASGPR Antibody (aa1-30, Azide-free, HRP) - LS-C251866 from LifeSpan Bioscience
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Anti-ASGR1 / ASGPR Antibody (aa1-30, Biotin) - LS-C251864 from LifeSpan Bioscience
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Anti-ASGR1 / ASGPR Antibody - LS-C285776 from LifeSpan Bioscience
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Anti-ASGR1 / ASGPR Antibody (FITC) - LS-C316685 from LifeSpan Bioscience
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Anti-ASGR1 / ASGPR Antibody (aa1-30) - LS-C319634 from LifeSpan Bioscience
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Anti-ASGR1 / ASGPR Antibody (HRP) - LS-C316688 from LifeSpan Bioscience
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Anti-ASGR1 / ASGPR Antibody (Biotin) - LS-C318716 from LifeSpan Bioscience
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