Gene Symbol | DAAM1 |
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Entrez Gene | 23002 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | dishevelled associated activator of morphogenesis 1 |
Other Description | disheveled-associated activator of morphogenesis 1 |
Swissprots | Q8N1Z8 Q8TB39 Q86U34 Q9Y4D1 |
Accessions | EAW80747 EAW80748 EAW80749 Q9Y4D1 AB014566 BAA31641 AK021890 BAG51056 AK093813 BAC04230 AK123651 AK291790 BAF84479 BC024781 AAH24781 BC038428 AAH38428 BC064999 AAH64999 BP199650 BQ050640 BX247986 CAD62320 BX648383 XM_005267430 XP_005267487 XM_005267431 XP_005267488 NM_001270520 NP_001257449 NM_014992 NP_055807 |
Function | Binds to disheveled (Dvl) and Rho, and mediates Wnt- induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments. {ECO:0000269|PubMed:16630611, ECO:0000269|PubMed:17482208}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16630611}. Note=Perinuclear. |
Tissue Specificity | Expressed in all tissues examined. |
Top Pathways | Wnt signaling pathway |
DAAM1 (E-13) - sc-55928 from Santa Cruz Biotechnology
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DAAM1 (K-16) - sc-55929 from Santa Cruz Biotechnology
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DAAM1 (H-55) - sc-135024 from Santa Cruz Biotechnology
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DAAM1 (N-17) - sc-55930 from Santa Cruz Biotechnology
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DAAM1 (WW-3) - sc-100942 from Santa Cruz Biotechnology
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Anti-DAAM1 antibody - ab56951 from Abcam
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Anti-DAAM1 antibody - ab84526 from Abcam
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Anti-DAAM1 antibody - Aminoterminal end - ab71327 from Abcam
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Anti-DAAM1 antibody - C-terminal - ab71499 from Abcam
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Anti-DAAM1 Antibody (aa341-370, Biotin) - LS-C234399 from LifeSpan Bioscience
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Anti-DAAM1 Antibody (aa341-370, APC) - LS-C234398 from LifeSpan Bioscience
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Anti-DAAM1 Antibody (aa341-370, PE) - LS-C234402 from LifeSpan Bioscience
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Anti-DAAM1 Antibody (aa341-370, FITC) - LS-C234400 from LifeSpan Bioscience
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Anti-DAAM1 Antibody (N-Terminus, AP) - LS-C244102 from LifeSpan Bioscience
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Anti-DAAM1 Antibody (aa1-50) - LS-C148369 from LifeSpan Bioscience
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Anti-DAAM1 Antibody (aa396-445) - LS-C102588 from LifeSpan Bioscience
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Anti-DAAM1 Antibody (N-Terminus, Biotin) - LS-C244103 from LifeSpan Bioscience
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Anti-DAAM1 Antibody (aa1034-1063) - LS-C98581 from LifeSpan Bioscience
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Anti-DAAM1 Antibody (N-Terminus, APC) - LS-C244104 from LifeSpan Bioscience
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Anti-DAAM1 Antibody (N-Terminus, FITC) - LS-C244105 from LifeSpan Bioscience
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Anti-DAAM1 Antibody (N-Terminus, PE) - LS-C244107 from LifeSpan Bioscience
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Anti-DAAM1 Antibody (N-Terminus, AP) - LS-C244106 from LifeSpan Bioscience
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Anti-DAAM1 Antibody (N-Terminus, APC) - LS-C244108 from LifeSpan Bioscience
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Anti-DAAM1 Antibody (N-Terminus, Biotin) - LS-C244109 from LifeSpan Bioscience
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Anti-DAAM1 Antibody (N-Terminus, FITC) - LS-C244110 from LifeSpan Bioscience
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