Gene Symbol | DAAM1 |
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Entrez Gene | 23002 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | dishevelled associated activator of morphogenesis 1 |
Other Description | disheveled-associated activator of morphogenesis 1 |
Swissprots | Q8N1Z8 Q8TB39 Q86U34 Q9Y4D1 |
Accessions | EAW80747 EAW80748 EAW80749 Q9Y4D1 AB014566 BAA31641 AK021890 BAG51056 AK093813 BAC04230 AK123651 AK291790 BAF84479 BC024781 AAH24781 BC038428 AAH38428 BC064999 AAH64999 BP199650 BQ050640 BX247986 CAD62320 BX648383 XM_005267430 XP_005267487 XM_005267431 XP_005267488 NM_001270520 NP_001257449 NM_014992 NP_055807 |
Function | Binds to disheveled (Dvl) and Rho, and mediates Wnt- induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments. {ECO:0000269|PubMed:16630611, ECO:0000269|PubMed:17482208}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16630611}. Note=Perinuclear. |
Tissue Specificity | Expressed in all tissues examined. |
Top Pathways | Wnt signaling pathway |
Human DAAM1 protein fragment - ab161497 from Abcam
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DAAM1 Antibody Blocking Peptide - LS-E7836 from LifeSpan Bioscience
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DAAM1 Antibody Blocking Peptide - LS-E7035 from LifeSpan Bioscience
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DAAM1 Antibody Blocking Peptide - LS-E7034 from LifeSpan Bioscience
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DAAM1 Antibody Blocking Peptide - LS-E19909 from LifeSpan Bioscience
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Recombinant Human DAAM1 Protein - H00023002-Q01 from Novus Biologicals
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DAAM1 Peptide - P1680 from Novus Biologicals
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DAAM1 Peptide - P1207 from Novus Biologicals
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DAAM1-Antibody-C-term-Blocking-Peptide - BP2720b from Abgent, a WuXi AppTec company
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DAAM1-Antibody-N-term-Blocking-Peptide - BP2720a from Abgent, a WuXi AppTec company
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Phospho-DAAM1T361-Antibody-Blocking-peptide - BP3550a from Abgent, a WuXi AppTec company
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DAAM1-T361-Antibody-N-term-Blocking-peptide - BP5439a from Abgent, a WuXi AppTec company
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DAAM1 Blocking Peptide - 33R-3460 from Fitzgerald
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DAAM1 - H00023002-Q01-10 from Acris Antibodies
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DAAM1 - H00023002-Q01-25 from Acris Antibodies
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DAAM1 fusion protein - Ag6648 from Proteintech Group
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DAAM1 fusion protein - Ag6809 from Proteintech Group
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Recombinant Human DAAM1, GST-tagged - DAAM1-11811H from Creative Biomart
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Recombinant Human Disheveled-associated activator of morphogenesis 1(DAAM1) ,par - CSB-YP896514HU CSB-EP896514HU CSB-BP896514HU CSB-MP896514HU from Cusabio
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DAAM1 - TP317675 from Acris Antibodies
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Recombinant Dishevelled Associated Activator Of Morphogenesis 1 (DAAM1) - RPC427Hu01 from Uscn Life Science Inc.
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Recombinant Dishevelled Associated Activator Of Morphogenesis 1 (DAAM1) - RPC427Hu01 from Cloud-clone
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DAAM1 Recombinant Protein Antigen - NBP1-81492PEP from Novus Biologicals
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DAAM1 Peptide, Human - M34GP04003H from Creative Peptides
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DAAM1 Blocking Peptide - CBP7533 from Cohesion Biosciences
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