SLX1B

Gene Symbol SLX1B
Entrez Gene 79008
Alt Symbol GIYD2
Species Human
Gene Type protein-coding
Description SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
Other Description GIY-YIG domain-containing protein 1|SLX1A|structure-specific endonuclease subunit SLX1
Swissprots Q9BQ83 Q6NTG6 B7ZME1
Accessions Q9BQ83 AK027092 BAB15654 AK225436 BC000754 AAH00754 BC000803 AAH00803 BC015990 AAH15990 BC019306 AAH19306 BC069007 AAH69007 BC130545 AAI30546 BC130547 AAI30548 NM_024044 NP_076949 NM_178044 NP_835145
Function Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. {ECO:0000255|HAMAP-Rule:MF_03100, ECO:0000269|PubMed:19595721, ECO:0000269|PubMed:19596235, ECO:0000269|PubMed:19596236}.
Subcellular Location Nucleus {ECO:0000255|HAMAP-Rule:MF_03100, ECO:0000269|PubMed:19596236}.
Top Pathways Fanconi anemia pathway

Anti-GIYD2 antibody - ab68807 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-GIYD2 antibody (ab68807) at 1/500 dilutionLane 1 : GIYD2 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-SLX1A / GIYD2 Antibody - LS-C308084 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-SLX1A / GIYD2 Antibody (aa13-62) - LS-C206002 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GIYD2 antibody Western Blot of Fetal Brain. Antibody dilution: 1 ug/ml.

Anti-SLX1A / GIYD2 Antibody (aa222-271) - LS-C206000 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GIYD2 antibody Western Blot of Fetal Lung. Antibody dilution: 1 ug/ml.

GIYD2 Antibody - H00079008-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: GIYD2 Antibody [H00079008-B01P] - Analysis of GIYD2 expression in transfected 293T cell line by GIYD2 polyclonal antibody. Lane 1: GIYD2 transfected lysate(30.25 KDa). Lane 2: Non-transfected lysate.

GIYD2 Polyclonal Antibody - bs-13361R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GIYD2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13361R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GIYD2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13361R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GIYD2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13361R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GIYD2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13361R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GIYD2 Polyclonal Antibody, Cy3 Conjugated - bs-13361R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GIYD2 Polyclonal Antibody, Cy5 Conjugated - bs-13361R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GIYD2 Polyclonal Antibody, Cy5.5 Conjugated - bs-13361R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GIYD2 Polyclonal Antibody, Cy7 Conjugated - bs-13361R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GIYD2 Polyclonal Antibody, FITC Conjugated - bs-13361R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GIYD2 Polyclonal Antibody, Biotin Conjugated - bs-13361R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GIYD2 Polyclonal Antibody, HRP Conjugated - bs-13361R-HRP from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SLX1B Antibody - C-terminal region (ARP71638_P050) - ARP71638_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SLX1B Antibody - N-terminal region (ARP71639_P050) - ARP71639_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GIYD2 Antibody - abx037323 from Abbexa

Host Rabbit
Clonality Polyclonal

GIYD2 antibody - STJ28896 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

GIYD2 antibody - 21158-1-AP from Proteintech Group

Prices $279.00
Sizes con: 59 μg/150μl
Host Rabbit
Clonality Polyclonal
mouse brain tissue were subjected to SDS PAGE followed by western blot with 21158-1-AP( GIYD2 Antibody) at dilution of 1:600

GIYD2 Antibody - E307386 from Enogene

Prices $275.00
Sizes 100ug/200ul

Anti-SLX1B monoclonal antibody - DCABH-200618 from Creative Diagnostics

Host Rabbit
Clonality Monoclonal
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