JTB

Gene Symbol JTB
Entrez Gene 10899
Alt Symbol HJTB, HSPC222, PAR, hJT
Species Human
Gene Type protein-coding
Description jumping translocation breakpoint
Other Description jumping translocation breakpoint protein|prostate androgen-regulated protein|protein JTB
Swissprots Q6IB19 O95442 O76095 Q9P0Q4
Accessions BAA33735 BAA33736 EAW53242 O76095 AB016488 BAA33731 AF115850 AAD09822 AF131797 AAD20045 AF151056 AAF36142 AK312106 BAG35042 BC000499 AAH00499 BC000996 AAH00996 BC001363 AAH01363 BC001667 AAH01667 BC004239 AAH04239 BC019277 AAH19277 BM907938 BT007285 AAP35949 BU527541 CR456985 CAG33266 NM_006694 NP_006685
Function Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity). Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential (By similarity). {ECO:0000250}.
Subcellular Location Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Mitochondrion {ECO:0000250}. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Detected at the centrosome and along spindle fibers during prophase and metaphase. Detected at the midbody during telophase.
Tissue Specificity Ubiquitous. Expressed in all normal human tissues studied but overexpressed or underexpressed in many of their malignant counterparts. {ECO:0000269|PubMed:10321732, ECO:0000269|PubMed:10762645, ECO:0000269|PubMed:17369841, ECO:0000269|PubMed:21225229}.

Protein JTB (JTB), Human, ELISA Kit - CSB-EL011970HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t
Sensitivity 4.68 pg/ml
Range 18.75 pg/ml-1200 pg/ml

jumping translocation breakpoint, ELISA Kit - MBS916563 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 4.68 pg/ml
Range 18.75 pg/ml-1200 pg/ml

Human Protein JTB(JTB) ELISA kit - CSB-EL011970HU from Cusabio

Category ELISA Kit
Sensitivity 4.68 pg/ml
Range 18.75 pg/ml-1200 pg/ml

Poly(ADP-ribose) Polymer/pADPr - 4336-100-01 from R&D Systems

Prices $192.00
Sizes 100 µl

ELISA Kit for Jumping Translocation Breakpoint Protein (JTB) - SEJ873Hu from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.056ng/mL.
Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Jumping Translocation Breakpoint Protein (JTB) - SEJ873Hu from Cloud-clone

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.056ng/mL.
Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human PAR ELISA Kit - abx572178 from Abbexa

Category ELISA Kit
Sensitivity 0.117 ng/ml
Range 0.313 ng/ml - 20 ng/ml

Human Jumping Translocation Breakpoint Protein (JTB) ELISA Kit - EKU09282 from Biomatik

Category ELISA Kit
Prices $735.00, $3,234.00, $5,880.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 0.056 ng/mL
Range 0.156-10 ng/mL

Human Protein JTB (JTB) ELISA Kit - EKC35217 from Biomatik

Category ELISA Kit
Prices $705.00, $2,820.00, $5,288.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 4.68 pg/ml
Range 18.75 pg/ml-1200 pg/ml

Human JTB ELISA Kit - E021199 from Biobool

Category ELISA Kit
Sensitivity 4.68 pg/ml

JTB ELISA Kit (Human) (OKCD02022) - OKCD02022 from Aviva Systems Biology

Category ELISA Kit
Prices $545.00
Sizes 96 wells
Sensitivity < 0.056 ng/mL
Range 0.156 - 10 ng/mL

Jumping Translocation Breakpoint Protein, ELISA Kit - MBS2031920 from MyBioSource

Category ELISA Kit
Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.056ng/mL.
Range 0.156-10ng/mL. The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.312ng/mL, 0.156ng/mL.

JTB, ELISA Kit - MBS285294 from MyBioSource

Category ELISA Kit
Prices $425.00, $720.00, $3,160.00, $6,055.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

JTB ELISA Kit (Human) (OKCA02135) - OKCA02135 from Aviva Systems Biology

Category ELISA Kit
Sensitivity 4.68 pg/mL
Range 18.75 pg/mL-1,200 pg/mL

Human JTB / PAR ELISA Kit (Sandwich ELISA) - LS-F39091 from LifeSpan Bioscience

Category ELISA Kit
Sensitivity 0.056
Range 0.156-10 ng/ml
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