MAP3K12

Gene Symbol	MAP3K12
Entrez Gene	7786
Alt Symbol	DLK, MEKK12, MUK, ZPK, ZPKP1
Species	Human
Gene Type	protein-coding
Description	mitogen-activated protein kinase kinase kinase 12
Other Description	MAPK-upstream kinase|dual leucine zipper bearing kinase|dual leucine zipper kinase DLK|leucine zipper protein kinase|mixed lineage kinase|protein kinase MUK
Swissprots	Q8WY25 Q86VQ5 B3KSS9 Q12852 G3V1Y2
Accessions	AAL67158 EAW96712 EAW96713 EAW96714 EAW96715 EAW96716 Q12852 AB209453 BAD92690 AK094195 BAG52841 AK314530 BC037585 BC050050 AAH50050 U07358 AAA67343 XM_005269138 XP_005269195 XM_005269140 XP_005269197 XM_006719588 XP_006719651 XM_006719589 XP_006719652 XM_011538725 XP_011537027 XM_011538726 XP_011537028 NM_001193511 NP_001180440 NM_006301 NP_006292
Function	May be an activator of the JNK/SAPK pathway. Phosphorylates beta-casein, histone 1 and myelin basic protein in vitro.
Subcellular Location	Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Tissue Specificity	Highly expressed in brain and kidney.
Top Pathways	MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MAP3K12 protein fragment - ab131688 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

MAP3K12 Antibody Blocking Peptide - LS-E8771 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP3K12 Blocking Peptide - NBP1-46063PEP from Novus Biologicals Category Peptide Prices $249.00 Sizes 250 µg Species Human

MAP3K12 Peptide - P2382 from Novus Biologicals Category Peptide Species Human

DLK-Antibody-C-term-D842-Blocking-Peptide - BP19279b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ZPK-Antibody-C-term-Blocking-Peptide - BP7214a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MAP3K12 - P5535 from Acris Antibodies Category Protein Prices $1,010.00 Sizes 5 µg Species Human

MAP3K12 fusion protein - ag4776 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

MAP3K12 fusion protein - Ag4780 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Mitogen Activated Protein Kinase Kinase Kinase 12 (MAP3K12) - RPD572Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

DLK protein-GST fusion - 009-001-R84 from Rockland Immunochemicals Inc Category Protein Prices $499.00 Sizes 50 µg Species Human

DLK protein-GST fusion - 009-001-R84S from Rockland Immunochemicals Inc Category Protein Prices $265.00 Sizes 20 µg Species Human

Recombinant Human Mitogen-activated protein kinase kinase kinase 12(MAP3K12) ,pa - CSB-YP013420HU CSB-EP013420HU CSB-BP013420HU CSB-MP013420HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MAP3K12 Protein - abx163240 from Abbexa Category Protein Species Human

MAP3K12 Recombinant Protein Antigen - NBP1-85013PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ZPK-Antibody-Center-Blocking-Peptide - BP7811a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MAP3K12 Peptide, Human - M34GP09168H from Creative Peptides Category Peptide Source Synthetic. Species Human

DLK, Recombinant Protein - MBS515116 from MyBioSource Category Protein Prices $260.00, $415.00 Sizes 20 µg, 50 µg Source Sf9 insect cells using baculovirus Species Human

Mitogen-activated protein kinase kinase kinase 12 (MAP3K12), partial, Recombinant Protein - MBS1323159 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

MAP3K12 Recombinant Protein Antigen - NBP2-58000PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Recombinant Human MAP3K12 protein, Flag-tagged, Biotinylated - MAP3K12-41H from Creative Biomart Category Protein Source Insect cell Species Human

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