MAP3K12

Gene Symbol MAP3K12
Entrez Gene 7786
Alt Symbol DLK, MEKK12, MUK, ZPK, ZPKP1
Species Human
Gene Type protein-coding
Description mitogen-activated protein kinase kinase kinase 12
Other Description MAPK-upstream kinase|dual leucine zipper bearing kinase|dual leucine zipper kinase DLK|leucine zipper protein kinase|mixed lineage kinase|protein kinase MUK
Swissprots Q8WY25 Q86VQ5 B3KSS9 Q12852 G3V1Y2
Accessions AAL67158 EAW96712 EAW96713 EAW96714 EAW96715 EAW96716 Q12852 AB209453 BAD92690 AK094195 BAG52841 AK314530 BC037585 BC050050 AAH50050 U07358 AAA67343 XM_005269138 XP_005269195 XM_005269140 XP_005269197 XM_006719588 XP_006719651 XM_006719589 XP_006719652 XM_011538725 XP_011537027 XM_011538726 XP_011537028 NM_001193511 NP_001180440 NM_006301 NP_006292
Function May be an activator of the JNK/SAPK pathway. Phosphorylates beta-casein, histone 1 and myelin basic protein in vitro.
Subcellular Location Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Tissue Specificity Highly expressed in brain and kidney.
Top Pathways MAPK signaling pathway

ZPK CRISPR/Cas9 KO Plasmid (h) - sc-404802 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZPK HDR Plasmid (h) - sc-404802-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZPK Double Nickase Plasmid (h) - sc-404802-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZPK Double Nickase Plasmid (h2) - sc-404802-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZPK CRISPR Activation Plasmid (h) - sc-404802-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZPK CRISPR Activation Plasmid (h2) - sc-404802-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZPK Lentiviral Activation Particles (h) - sc-404802-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZPK Lentiviral Activation Particles (h2) - sc-404802-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZPK siRNA (h) - sc-39259 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZPK shRNA Plasmid (h) - sc-39259-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZPK shRNA (h) Lentiviral Particles - sc-39259-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU074721 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® siRNA - SIHK1129 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1131 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1130 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN12989 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12989 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MAP3K12 siRNA (Human) - CRH5273 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MAP3K12 RNAi - H00007786-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human MAP3K12 (NM_006301.3) - SHH337643 from Creative biogene

Category siRNA
Species Reactivities Human

Human MAP3K12 siRNA - orb265775 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MAP3K12 shRNA Plasmid (Human) - CHH5273 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MAP3K12 miRNA 3'UTR clone - MiUTR3H-03383 from Creative biogene

Species Reactivities Human
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