MYH9

Gene Symbol	MYH9
Entrez Gene	4627
Alt Symbol	BDPLT6, DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHC-IIA, NMMHCA
Species	Human
Gene Type	protein-coding
Description	myosin, heavy chain 9, non-muscle
Other Description	cellular myosin heavy chain, type A|myosin-9|non-muscle myosin heavy chain A|non-muscle myosin heavy chain IIa|non-muscle myosin heavy polypeptide 9|nonmuscle myosin heavy chain II-A
Swissprots	P35579 Q86T83 Q60FE2 A8K6E4 O60805
Accessions	ABC25483 CBX47535 EAW60096 EAW60097 EAW60098 P35579 AA420536 AB191263 BAD52439 AB290175 BAG06729 AK025219 AK025393 AK131080 BAC85130 AK291609 BAF84298 AK304840 BAG65583 AL832639 CAD89954 BC011915 BC049849 AAH49849 BC090921 AAH90921 BC111387 BC150169 AAI50170 BC150170 AAI50171 CD614930 CR456526 CAG30412 CU013126 CAK54557 CU013414 CAK54856 D11393 BAA01989 DC296130 L29141 AAA20904 M31013 AAA36349 M69180 AAA61765 M81105 AAA59888 XM_011530197 XP_011528499 NM_002473 NP_002464
Function	Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10. {ECO:0000269|PubMed:20052411}.
Subcellular Location	Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cell cortex {ECO:0000250}. Note=Colocalizes with actin filaments at lamellipodia margins and at the leading edge of migrating cells. {ECO:0000269|PubMed:20052411}.
Tissue Specificity	In the kidney, expressed in the glomeruli. Also expressed in leukocytes. {ECO:0000269|PubMed:11752022, ECO:0000269|PubMed:1912569}.
Top Pathways	Tight junction, Salmonella infection, Regulation of actin cytoskeleton

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human non-muscle Myosin IIA peptide - ab99161 from Abcam Category Peptide

Human non-muscle Myosin IIA peptide - ab99879 from Abcam Category Peptide

MYH9 Antibody Blocking Peptide - LS-E5586 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MYH9 Antibody Blocking Peptide - LS-E17395 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human non-muscle Myosin IIA Protein - H00004627-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

non-muscle Myosin IIA Partial Recombinant Protein - H00004627-Q02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

MYH9-Antibody-N-term-Y158-Blocking-Peptide - BP16804a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MYH9-Antibody-C-term-Blocking-Peptide - BP18112b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant human Myosin-9 (OPCA00390) - OPCA00390 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

MYH9 Blocking Peptide - 33R-1860 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MYH9 protein - 30R-3272 from Fitzgerald Category Protein Prices $210.00 Sizes 50 µg Source E.coli

Myosin-9 / MYH9 - H00004627-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Myosin-9 / MYH9 - H00004627-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Myosin-9 / MYH9 - H00004627-Q02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

Myosin-9 / MYH9 - H00004627-Q02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Myosin-9 / MYH9 - H00004627-Q02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MYH9 fusion protein - Ag1612 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

MYH9 fusion protein - ag17971 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human MYH9, His-tagged - MYH9-29659TH from Creative Biomart Category Protein Source E. coli

Recombinant Human MYH9, GST-tagged - MYH9-29H from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant Human MYH9, GST-tagged - MYH9-31H from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant Human MYH9, GST-tagged - MYH9-30H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Myosin Heavy Chain 9, Non Muscle (MYH9) - RPD422Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Myosin 9 Blocking Peptide - CBP2988 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Dog, Pig

Recombinant Myosin Heavy Chain 9, Non Muscle (MYH9) - RPD422Hu01 from Cloud-clone Category Protein Source E.coli Species Human

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