MYH9

Gene Symbol MYH9
Entrez Gene 4627
Alt Symbol BDPLT6, DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHC-IIA, NMMHCA
Species Human
Gene Type protein-coding
Description myosin, heavy chain 9, non-muscle
Other Description cellular myosin heavy chain, type A|myosin-9|non-muscle myosin heavy chain A|non-muscle myosin heavy chain IIa|non-muscle myosin heavy polypeptide 9|nonmuscle myosin heavy chain II-A
Swissprots P35579 Q86T83 Q60FE2 A8K6E4 O60805
Accessions ABC25483 CBX47535 EAW60096 EAW60097 EAW60098 P35579 AA420536 AB191263 BAD52439 AB290175 BAG06729 AK025219 AK025393 AK131080 BAC85130 AK291609 BAF84298 AK304840 BAG65583 AL832639 CAD89954 BC011915 BC049849 AAH49849 BC090921 AAH90921 BC111387 BC150169 AAI50170 BC150170 AAI50171 CD614930 CR456526 CAG30412 CU013126 CAK54557 CU013414 CAK54856 D11393 BAA01989 DC296130 L29141 AAA20904 M31013 AAA36349 M69180 AAA61765 M81105 AAA59888 XM_011530197 XP_011528499 NM_002473 NP_002464
Function Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10. {ECO:0000269|PubMed:20052411}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cell cortex {ECO:0000250}. Note=Colocalizes with actin filaments at lamellipodia margins and at the leading edge of migrating cells. {ECO:0000269|PubMed:20052411}.
Tissue Specificity In the kidney, expressed in the glomeruli. Also expressed in leukocytes. {ECO:0000269|PubMed:11752022, ECO:0000269|PubMed:1912569}.
Top Pathways Tight junction, Salmonella infection, Regulation of actin cytoskeleton

Phospho-Myosin IIa (Ser1943) (D7Z7T) Rabbit mAb - 14611 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D7Z7T
Western blot analysis of extracts from various cell lines, untreated (-) or treated with λ phosphatase and calf intestinal phosphatase (CIP; +), using Phospho-Myosin IIa (Ser1943) (D7Z7T) Rabbit mAb (upper) and Myosin IIa Antibody #3403 (lower).

Phospho-Myosin IIa (Ser1943) Antibody - 5026 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HeLa, A-431 and 293T cells, untreated or treated with λ phosphatase and calf intestinal phosphatase (CIP), using Phospho-Myosin IIa (Ser1943) Antibody (upper) or Myosin IIa Antibody #3403 (lower).

Myosin IIa Antibody - 3403 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell types using Myosin IIa Antibody.

MYH2 (6D596) - sc-71631 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MYH2 (6D596): sc-71631. Western blot analysis of MYH2 expression in RD whole cell lysate.

MYH9 (D-16) - sc-47199 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MYH9 (D-16): sc-47199. Western blot analysis of MYH9 expression in Caki-1 (A) and RD (B) whole cell lysates.

MYH9 (G-12) - sc-47200 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MYH9 (G-12): sc-47200. Western blot analysis of MYH9 expression in Jurkat (A), HUV-EC-C (B) and A431 (C) whole cell lysates.

MYH9 (H-40) - sc-98978 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MYH9 (H-40): sc-98978. Western blot analysis of MYH9 expression in rat skeletal muscle tissue extract.

MYH9 (K-19) - sc-47201 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MYH9 (K-19): sc-47201. Western blot analysis of MYH9 expression in Hep G2 (A), HeLa (B), Jurkat (C) and HUV-EC-C (D) whole cell lysates.

Myosin IIa (6D595) - sc-71632 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MYH2 (6D595): sc-71632. Western blot analysis of MYH2 expression in rat skeletal tissue extract.

Anti-non-muscle Myosin IIA antibody - ab55456 from Abcam

Prices $403.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab55456 non-muscle Myosin IIA antibody at 1ug/ml.

Anti-non-muscle Myosin IIA antibody [2B3] - ab122978 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2B3
Immunohistochemistry of Formalin-Fixed, Paraffin-Embedded Human Breast tissue with ab122978 at 5µg/ml.

Anti-non-muscle Myosin IIA antibody [4H3] - ab117572 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 4H3
Immunohistochemical analysis of non-muscle Myosin IIA in Formalin-Fixed, Paraffin-Embedded Human Kidney, Glomeruli, using 5 µg/ml ab117572.

Anti-non-muscle Myosin IIA antibody [EPR8965] - ab138498 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8965
All lanes : Anti-non-muscle Myosin IIA antibody [EPR8965] (ab138498) at 1/1000 dilutionLane 1 : HeLa lysateLane 2 : HT-29 lysateLane 3 : Jurkat lysateLane 4 : HUVEC lysateLane 5 : Human fetal kidney lysateLane 6 : A431 lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-MYH9 Antibody (C-Terminus) - LS-C189115 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-MYH9 Antibody (phospho-Ser1943) - LS-C190115 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MYH9 Antibody (phospho-Tyr158) - LS-C163645 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Dot blot of Phospho-MYH9-Y158 Antibody Phospho-specific antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.

Anti-MYH9 Antibody (HRP) - LS-C211839 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MYH9 Antibody - LS-C211840 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MYH9 Antibody (FITC) - LS-C211842 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MYH9 Antibody (Biotin) - LS-C211843 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MYH9 Antibody (phospho-Tyr158, AP) - LS-C215890 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MYH9 Antibody (phospho-Tyr158, Biotin) - LS-C215892 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MYH9 Antibody (phospho-Tyr158, APC) - LS-C215891 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MYH9 Antibody (phospho-Tyr158, PE) - LS-C215896 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MYH9 Antibody (phospho-Tyr158, FITC) - LS-C215895 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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