MYH9

Gene Symbol MYH9
Entrez Gene 4627
Alt Symbol BDPLT6, DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHC-IIA, NMMHCA
Species Human
Gene Type protein-coding
Description myosin, heavy chain 9, non-muscle
Other Description cellular myosin heavy chain, type A|myosin-9|non-muscle myosin heavy chain A|non-muscle myosin heavy chain IIa|non-muscle myosin heavy polypeptide 9|nonmuscle myosin heavy chain II-A
Swissprots P35579 Q86T83 Q60FE2 A8K6E4 O60805
Accessions ABC25483 CBX47535 EAW60096 EAW60097 EAW60098 P35579 AA420536 AB191263 BAD52439 AB290175 BAG06729 AK025219 AK025393 AK131080 BAC85130 AK291609 BAF84298 AK304840 BAG65583 AL832639 CAD89954 BC011915 BC049849 AAH49849 BC090921 AAH90921 BC111387 BC150169 AAI50170 BC150170 AAI50171 CD614930 CR456526 CAG30412 CU013126 CAK54557 CU013414 CAK54856 D11393 BAA01989 DC296130 L29141 AAA20904 M31013 AAA36349 M69180 AAA61765 M81105 AAA59888 XM_011530197 XP_011528499 NM_002473 NP_002464
Function Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10. {ECO:0000269|PubMed:20052411}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cell cortex {ECO:0000250}. Note=Colocalizes with actin filaments at lamellipodia margins and at the leading edge of migrating cells. {ECO:0000269|PubMed:20052411}.
Tissue Specificity In the kidney, expressed in the glomeruli. Also expressed in leukocytes. {ECO:0000269|PubMed:11752022, ECO:0000269|PubMed:1912569}.
Top Pathways Tight junction, Salmonella infection, Regulation of actin cytoskeleton

MYH9 CRISPR/Cas9 KO Plasmid (h) - sc-401182 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYH9 HDR Plasmid (h) - sc-401182-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYH9 Double Nickase Plasmid (h) - sc-401182-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYH9 Double Nickase Plasmid (h2) - sc-401182-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYH9 CRISPR Activation Plasmid (h) - sc-401182-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYH9 CRISPR Activation Plasmid (h2) - sc-401182-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYH9 Lentiviral Activation Particles (h) - sc-401182-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYH9 Lentiviral Activation Particles (h2) - sc-401182-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYH9 siRNA (h) - sc-61120 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MYH9 shRNA Plasmid (h) - sc-61120-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MYH9 shRNA (h) Lentiviral Particles - sc-61120-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

non-muscle Myosin IIA RNAi - H00004627-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU081611 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2088 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2088 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MYH9 siRNA (Human) - CRH3054 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MYH9 (NM_002473.4) - SHH347860 from Creative biogene

Category siRNA
Species Reactivities Human

Human MYH9 siRNA - orb263556 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MYH9 shRNA Plasmid (Human) - CHH3054 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MYH9 miRNA 3'UTR clone - MiUTR3H-01491 from Creative biogene

Species Reactivities Human
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