NDRG4

Gene Symbol NDRG4
Entrez Gene 65009
Alt Symbol BDM1, SMAP-8, SMAP8
Species Human
Gene Type protein-coding
Description NDRG family member 4
Other Description N-myc downstream-regulated gene 4 protein|brain development-related molecule 1|protein NDRG4|smooth muscle-associated protein 8|vascular smooth muscle cell-associated protein 8
Swissprots Q9GZM1 Q9GZN3 Q96PL9 B4DSW5 B3KNU2 Q9GZX0 Q6ZTI7 H7C600 B4DK66 Q9ULP0 Q6ZNE7
Accessions BAB20071 BAB20072 BAB20073 EAW82977 EAW82978 EAW82979 Q9ULP0 AB021172 BAB20288 AB033006 BAA86494 AB044944 BAB20068 AB044945 BAB20069 AB044946 BAB20070 AF007138 AF308608 AAL08806 AK055038 BAG51454 AK055148 AK124005 AK126574 BAC86600 AK126729 BAG54366 AK131248 BAD18428 AK296415 BAG59078 AK299949 BAG61777 AK316089 BAH14460 AL136584 CAB66519 AM393094 CAL37972 AM393323 CAL38201 BC001527 BC011795 AAH11795 CF552009 CR936733 DA069318 DA099057 DA242460 DB498690 EU832826 ACE87837 GQ129230 ACT64364 XM_006721252 XP_006721315 XM_006721253 XP_006721316 XM_006721254 XP_006721317 XM_006721256 XP_006721319 XM_006721257 XP_006721320 XM_006721258 XP_006721321 XM_006721259 XP_006721322 XM_006721260 XP_006721323 XM_006721261 XP_006721324 XM_006721262 XP_006721325 XM_011523290 XP_011521592 XM_011523291 XP_011521593 XM_011523292 XP_011521594 XM_011523293 XP_011521595 XM_011523294 XP_011521596 NM_001130487 NP_001123959 NM_001242833 NP_001229762 NM_001242834 NP_001229763 NM_001242835 NP_001229764 NM_001242836 NP_001229765 NM_020465 NP_065198 NM_022910 NP_075061 NR_040072
Function Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress (By similarity). May enhance growth factor-induced ERK1 and ERK2 phosphorylation, including that induced by PDGF and FGF. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner. {ECO:0000250, ECO:0000269|PubMed:12755708}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:12755708, ECO:0000269|PubMed:19592488}.
Tissue Specificity Expressed predominantly in brain and heart (at protein level). In the brain, detected in astrocytes. Isoform 1 and isoform 2 are only expressed in brain. Isoform 3 is expressed in both heart and brain. Up-regulated in glioblastoma multiforme cells. {ECO:0000269|PubMed:11352569, ECO:0000269|PubMed:12755708, ECO:0000269|PubMed:19592488}.

NDRG4 (D4A6) Rabbit mAb - 9039 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D4A6
Western blot analysis of extracts from human cerebellum, mouse brain, and rat brain using NDRG4 (D4A6) Rabbit mAb.

NDRG4 (B-10) - sc-393342 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NDRG4 (B-10): sc-393342. Western blot analysis of NDRG4 expression in non-transfected: sc-117752 (A) and human NDRG4 transfected: sc-129235 (B) 293T whole cell lysates.

NDRG4 (C-8) - sc-514144 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NDRG4 (C-8): sc-514144. Western blot analysis of NDRG4 expression in non-transfected 293T: sc-117752 (A), human NDRG4 transfected 293T: sc-129235 (B), Jurkat (C), CCRF-CEM (D), Hep G2 (E) and IMR-32 (F) whole cell lysates.

NDRG4 (C-14) - sc-165090 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NDRG4 (C-14): sc-165090. Western blot analysis of NDRG4 expression in non-transfected: sc-117752 (A) and human NDRG4 transfected: sc-129235 (B) 293T whole cell lysates.

NDRG4 (E-14) - sc-165092 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NDRG4 (E-14): sc-165092. Western blot analysis of NDRG4 expression in mouse kidney tissue extract.

NDRG4 (39-V) - sc-100788 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
NDRG4 (39-V): sc-100788. Western blot analysis of NDRG4 expression in Raw 264.7 whole cell lysate.

Anti-NDRG4 antibody - ab126245 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-NDRG4 antibody (ab126245) at 1/1000 dilution + Jurkat whole cell lysate at 30 µg

Anti-NDRG4 antibody - ab130574 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-NDRG4 antibody (ab130574) at 1/100 dilution + CEM cell line lysate at 35 µg

Anti-NDRG4 antibody [2G3] - ab131136 from Abcam

Prices $407.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2G3
Immunohistochemical analysis of Formalin-Fixed, Paraffin-Embedded Human brain cortex tissue NDRG4 with ab131136 at 1/100 dilution.

Anti-NDRG4 antibody - Carboxyterminal end - ab63990 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NDRG4 Antibody (C-Terminus) - LS-C144717 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NDRG4 Antibody (N-Terminus) - LS-C151806 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
NDRG4 antibody Western Blot of PANC1.

Anti-NDRG4 Antibody - LS-C155520 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: Jurkat 10% SDS PAGE NDRG4 antibody diluted at 1:1000

Anti-NDRG4 Antibody (aa187-236) - LS-C120258 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HT-29/HepG2 cells, using NDRG4 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-NDRG4 Antibody (aa193-220, AP) - LS-C264130 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NDRG4 Antibody (aa193-220, APC) - LS-C264131 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NDRG4 Antibody (aa193-220, Biotin) - LS-C264132 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NDRG4 Antibody (aa193-220, FITC) - LS-C264133 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NDRG4 Antibody (aa168-217) - LS-C200258 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from K562 cells using NDRG4 antibody.

Anti-NDRG4 Antibody (aa193-220, Azide-free, HRP) - LS-C264134 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NDRG4 Antibody (aa193-220) - LS-C164791 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
NDRG4 Antibody western blot of CEM cell line lysates (35 ug/lane). The NDRG4 antibody detected the NDRG4 protein (arrow).

Anti-NDRG4 Antibody (aa193-220, PE) - LS-C264136 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NDRG4 Antibody (aa192-220) - LS-C323262 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NDRG4 Antibody (aa1-340, Azide-free) - LS-C328044 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-NDRG4 Antibody (C-Terminus) - LS-C187327 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Fetal Liver. NDRG4 antibody dilution 1.0 ug/ml.
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