NDRG4

Gene Symbol	NDRG4
Entrez Gene	65009
Alt Symbol	BDM1, SMAP-8, SMAP8
Species	Human
Gene Type	protein-coding
Description	NDRG family member 4
Other Description	N-myc downstream-regulated gene 4 protein|brain development-related molecule 1|protein NDRG4|smooth muscle-associated protein 8|vascular smooth muscle cell-associated protein 8
Swissprots	Q9GZM1 Q9GZN3 Q96PL9 B4DSW5 B3KNU2 Q9GZX0 Q6ZTI7 H7C600 B4DK66 Q9ULP0 Q6ZNE7
Accessions	BAB20071 BAB20072 BAB20073 EAW82977 EAW82978 EAW82979 Q9ULP0 AB021172 BAB20288 AB033006 BAA86494 AB044944 BAB20068 AB044945 BAB20069 AB044946 BAB20070 AF007138 AF308608 AAL08806 AK055038 BAG51454 AK055148 AK124005 AK126574 BAC86600 AK126729 BAG54366 AK131248 BAD18428 AK296415 BAG59078 AK299949 BAG61777 AK316089 BAH14460 AL136584 CAB66519 AM393094 CAL37972 AM393323 CAL38201 BC001527 BC011795 AAH11795 CF552009 CR936733 DA069318 DA099057 DA242460 DB498690 EU832826 ACE87837 GQ129230 ACT64364 XM_006721252 XP_006721315 XM_006721253 XP_006721316 XM_006721254 XP_006721317 XM_006721256 XP_006721319 XM_006721257 XP_006721320 XM_006721258 XP_006721321 XM_006721259 XP_006721322 XM_006721260 XP_006721323 XM_006721261 XP_006721324 XM_006721262 XP_006721325 XM_011523290 XP_011521592 XM_011523291 XP_011521593 XM_011523292 XP_011521594 XM_011523293 XP_011521595 XM_011523294 XP_011521596 NM_001130487 NP_001123959 NM_001242833 NP_001229762 NM_001242834 NP_001229763 NM_001242835 NP_001229764 NM_001242836 NP_001229765 NM_020465 NP_065198 NM_022910 NP_075061 NR_040072
Function	Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress (By similarity). May enhance growth factor-induced ERK1 and ERK2 phosphorylation, including that induced by PDGF and FGF. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner. {ECO:0000250, ECO:0000269|PubMed:12755708}.
Subcellular Location	Cytoplasm, cytosol {ECO:0000269|PubMed:12755708, ECO:0000269|PubMed:19592488}.
Tissue Specificity	Expressed predominantly in brain and heart (at protein level). In the brain, detected in astrocytes. Isoform 1 and isoform 2 are only expressed in brain. Isoform 3 is expressed in both heart and brain. Up-regulated in glioblastoma multiforme cells. {ECO:0000269|PubMed:11352569, ECO:0000269|PubMed:12755708, ECO:0000269|PubMed:19592488}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

NDRG4-Over-expression-Lysate - LY14830a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

NDRG4 overexpression lysate - LY427222 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

NDRG4 293 Cell Lysate - 402427 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

NDRG4 Overexpression Lysate (Native) - NBL1-13532 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

NDRG4 Overexpression Lysate (Native) - NBP2-06376 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

NDRG4 (h): 293T Lysate - sc-129236 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

NDRG4 (h2): 293T Lysate - sc-129235 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

NDRG4 (h3): 293T Lysate - sc-177608 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

NDRG4 Over-expression Lysate Product - GWB-550ECE from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

NDRG4 Overexpression Lysate (Native) - NBP2-09514 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human NDRG4 Knockdown Stable Cell Line - CSC-DC010222 from Creative biogene Category Cell Line Species Human

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