NDRG4

Gene Symbol NDRG4
Entrez Gene 65009
Alt Symbol BDM1, SMAP-8, SMAP8
Species Human
Gene Type protein-coding
Description NDRG family member 4
Other Description N-myc downstream-regulated gene 4 protein|brain development-related molecule 1|protein NDRG4|smooth muscle-associated protein 8|vascular smooth muscle cell-associated protein 8
Swissprots Q9GZM1 Q9GZN3 Q96PL9 B4DSW5 B3KNU2 Q9GZX0 Q6ZTI7 H7C600 B4DK66 Q9ULP0 Q6ZNE7
Accessions BAB20071 BAB20072 BAB20073 EAW82977 EAW82978 EAW82979 Q9ULP0 AB021172 BAB20288 AB033006 BAA86494 AB044944 BAB20068 AB044945 BAB20069 AB044946 BAB20070 AF007138 AF308608 AAL08806 AK055038 BAG51454 AK055148 AK124005 AK126574 BAC86600 AK126729 BAG54366 AK131248 BAD18428 AK296415 BAG59078 AK299949 BAG61777 AK316089 BAH14460 AL136584 CAB66519 AM393094 CAL37972 AM393323 CAL38201 BC001527 BC011795 AAH11795 CF552009 CR936733 DA069318 DA099057 DA242460 DB498690 EU832826 ACE87837 GQ129230 ACT64364 XM_006721252 XP_006721315 XM_006721253 XP_006721316 XM_006721254 XP_006721317 XM_006721256 XP_006721319 XM_006721257 XP_006721320 XM_006721258 XP_006721321 XM_006721259 XP_006721322 XM_006721260 XP_006721323 XM_006721261 XP_006721324 XM_006721262 XP_006721325 XM_011523290 XP_011521592 XM_011523291 XP_011521593 XM_011523292 XP_011521594 XM_011523293 XP_011521595 XM_011523294 XP_011521596 NM_001130487 NP_001123959 NM_001242833 NP_001229762 NM_001242834 NP_001229763 NM_001242835 NP_001229764 NM_001242836 NP_001229765 NM_020465 NP_065198 NM_022910 NP_075061 NR_040072
Function Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress (By similarity). May enhance growth factor-induced ERK1 and ERK2 phosphorylation, including that induced by PDGF and FGF. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner. {ECO:0000250, ECO:0000269|PubMed:12755708}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:12755708, ECO:0000269|PubMed:19592488}.
Tissue Specificity Expressed predominantly in brain and heart (at protein level). In the brain, detected in astrocytes. Isoform 1 and isoform 2 are only expressed in brain. Isoform 3 is expressed in both heart and brain. Up-regulated in glioblastoma multiforme cells. {ECO:0000269|PubMed:11352569, ECO:0000269|PubMed:12755708, ECO:0000269|PubMed:19592488}.

NDRG4 CRISPR/Cas9 KO Plasmid (h) - sc-417898 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDRG4 HDR Plasmid (h) - sc-417898-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDRG4 Double Nickase Plasmid (h) - sc-417898-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDRG4 Double Nickase Plasmid (h2) - sc-417898-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDRG4 CRISPR Activation Plasmid (h) - sc-417898-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDRG4 CRISPR Activation Plasmid (h2) - sc-417898-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDRG4 Lentiviral Activation Particles (h) - sc-417898-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDRG4 Lentiviral Activation Particles (h2) - sc-417898-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDRG4 siRNA (h) - sc-93374 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NDRG4 shRNA Plasmid (h) - sc-93374-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NDRG4 shRNA (h) Lentiviral Particles - sc-93374-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NDRG4 RNAi - H00065009-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU139771 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15129 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15129 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

NDRG4 siRNA (Human) - CRJ2163 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NDRG4 RNAi - H00065009-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human NDRG4 (NM_022910.3) - SHH350400 from Creative biogene

Category siRNA
Species Reactivities Human

Human NDRG4 siRNA - orb272664 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NDRG4 shRNA Plasmid (Human) - CHJ2163 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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