NDRG4

Gene Symbol NDRG4
Entrez Gene 65009
Alt Symbol BDM1, SMAP-8, SMAP8
Species Human
Gene Type protein-coding
Description NDRG family member 4
Other Description N-myc downstream-regulated gene 4 protein|brain development-related molecule 1|protein NDRG4|smooth muscle-associated protein 8|vascular smooth muscle cell-associated protein 8
Swissprots Q9GZM1 Q9GZN3 Q96PL9 B4DSW5 B3KNU2 Q9GZX0 Q6ZTI7 H7C600 B4DK66 Q9ULP0 Q6ZNE7
Accessions BAB20071 BAB20072 BAB20073 EAW82977 EAW82978 EAW82979 Q9ULP0 AB021172 BAB20288 AB033006 BAA86494 AB044944 BAB20068 AB044945 BAB20069 AB044946 BAB20070 AF007138 AF308608 AAL08806 AK055038 BAG51454 AK055148 AK124005 AK126574 BAC86600 AK126729 BAG54366 AK131248 BAD18428 AK296415 BAG59078 AK299949 BAG61777 AK316089 BAH14460 AL136584 CAB66519 AM393094 CAL37972 AM393323 CAL38201 BC001527 BC011795 AAH11795 CF552009 CR936733 DA069318 DA099057 DA242460 DB498690 EU832826 ACE87837 GQ129230 ACT64364 XM_006721252 XP_006721315 XM_006721253 XP_006721316 XM_006721254 XP_006721317 XM_006721256 XP_006721319 XM_006721257 XP_006721320 XM_006721258 XP_006721321 XM_006721259 XP_006721322 XM_006721260 XP_006721323 XM_006721261 XP_006721324 XM_006721262 XP_006721325 XM_011523290 XP_011521592 XM_011523291 XP_011521593 XM_011523292 XP_011521594 XM_011523293 XP_011521595 XM_011523294 XP_011521596 NM_001130487 NP_001123959 NM_001242833 NP_001229762 NM_001242834 NP_001229763 NM_001242835 NP_001229764 NM_001242836 NP_001229765 NM_020465 NP_065198 NM_022910 NP_075061 NR_040072
Function Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress (By similarity). May enhance growth factor-induced ERK1 and ERK2 phosphorylation, including that induced by PDGF and FGF. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner. {ECO:0000250, ECO:0000269|PubMed:12755708}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:12755708, ECO:0000269|PubMed:19592488}.
Tissue Specificity Expressed predominantly in brain and heart (at protein level). In the brain, detected in astrocytes. Isoform 1 and isoform 2 are only expressed in brain. Isoform 3 is expressed in both heart and brain. Up-regulated in glioblastoma multiforme cells. {ECO:0000269|PubMed:11352569, ECO:0000269|PubMed:12755708, ECO:0000269|PubMed:19592488}.

Human NDRG4 full length protein - ab163915 from Abcam

Category Protein
Source Wheat germ
Species Human
ab163915 on a 12.5% SDS-PAGE stained with Coomassie Blue.

NDRG4 Antibody Blocking Peptide - LS-E4720 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

NDRG4 Antibody Blocking Peptide - LS-E23604 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

NDRG4 Antibody Blocking Peptide - LS-E23605 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human NDRG4 Protein - H00065009-P01 from Novus Biologicals

Category Protein
Prices $305.00, $445.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

NDRG4-Antibody-Center-Blocking-Peptide - BP17090c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

NDRG4 - H00065009-P01-02 from Acris Antibodies

Category Protein
Prices $300.00
Sizes 2 µg
Source in vitro transl.
Species Human

NDRG4 fusion protein - ag3029 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

NDRG4 (G217) Peptide - BS3378P from Bioworld Technology

Category Peptide
Prices $158.00
Sizes 100 µl

Recombinant Human Protein NDRG4(NDRG4) - CSB-YP890932HU CSB-EP890932HU CSB-BP890932HU CSB-MP890932HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

NDRG4 Peptide - abx164806 from Abbexa

Category Peptide
Species Human, Mouse, Rat

NDRG4 (transcript variant 1) - TP321058 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
NDRG4

NDRG4 (transcript variant 3) - TP321301 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
NDRG4

NDRG4 Recombinant Protein Antigen - NBP1-81434PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

NDRG4 Protein - NBP1-81433PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

NDRG4 Blocking Peptide - abx061313 from Abbexa

Category Peptide
Species Human, Mouse, Rat

NDRG4 Peptide, Human - M34GP10222H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

NDRG4 Blocking Peptide - CBP5226 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat

NDRG4 Antibody - SH-A13926 from Novatein Biosciences

Prices $315.00
Sizes 100 µl
Species Human, Mouse, Rat

Protein NDRG4 (NDRG4), Recombinant Protein - MBS1389627 from MyBioSource

Category Protein
Prices $1,115.00, $1,115.00, $1,345.00, $1,345.00, $1,770.00, $1,770.00, $2,235.00, $2,235.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

Recombinant Human NDRG4 Protein, His-tagged - NDRG4-520H from Creative Biomart

Category Protein
Source E. coli
Species Human
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