MARCKSL1

Gene Symbol MARCKSL1
Entrez Gene 65108
Alt Symbol F52, MACMARCKS, MLP, MLP1, MRP
Species Human
Gene Type protein-coding
Description MARCKS-like 1
Other Description MARCKS-like protein 1|MARCKS-related protein|mac-MARCKS|macrophage myristoylated alanine-rich C kinase substrate
Swissprots Q5TEE6 D3DPQ0 Q6NXS5 P49006
Accessions AAP37955 EAX07537 EAX07538 EAX07539 P49006 AI879076 AL713653 CAD28462 AM393505 CAL38382 AY007131 BC007904 AAH07904 BC066915 AAH66915 DQ893237 ABM84163 DQ896567 ABM87566 DT218825 N70661 X70326 CAA49793 NM_023009 NP_075385 NR_052852
Function Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May also affect cancer cell migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Associates with the membrane via the insertion of the N-terminal N-myristoyl chain and the partial insertion of the effector domain. Association of the effector domain with membranes may be regulated by Ca(2+)/calmodulin (By similarity). In prostate cancers, detected in the cytoplasm and associated with apical or basal membranes (By similarity). {ECO:0000250}.
Top Pathways Fc gamma R-mediated phagocytosis, Leishmaniasis

MARCKSL1 (H-163) - sc-292783 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

MARCKSL1 (P-12) - sc-161829 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MARCKSL1 (I-23) - sc-130167 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
MARCKSL1 (I-23): sc-130167. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cancer tissue showing cytoplasmic staining.

MARCKSL1 (K53) - sc-130471 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
MARCKSL1 (K53): sc-130471. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human testis tissue showing cytoplasmic and membrane localization.

Anti-MARCKS like protein antibody - ab200711 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MARCKS like protein antibody (ab200711)Lane 1 : HEK293T whole cell lysateLane 2 : mouse Raw 264.7 whole cell lysateLane 3 : rat PC12 whole cell lysate

Anti-MARCKS like protein antibody [EPR15353] - C-terminal - ab184546 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15353
All lanes : Anti-MARCKS like protein antibody [EPR15353] - C-terminal (ab184546) at 1/10000 dilutionLane 1 : 293T cell lysateLane 2 : SH-SY5Y cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-MARCKS like protein antibody - ab57596 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57596 MARCKS like protein antibody at 1ug/ml.

Anti-MARCKS like protein antibody - ab128622 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MARCKS like protein antibody (ab128622) at 1 µg/ml + 293T cell lysate at 10 µg

Anti-MARCKSL1 Antibody (aa131-160, AP) - LS-C262653 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MARCKSL1 Antibody (aa131-160, APC) - LS-C262654 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MARCKSL1 Antibody (aa131-160, Biotin) - LS-C262655 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MARCKSL1 Antibody (aa131-160, FITC) - LS-C262656 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MARCKSL1 Antibody (aa131-160, Azide-free, HRP) - LS-C262657 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MARCKSL1 Antibody (aa131-160, PE) - LS-C262658 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MARCKSL1 Antibody (aa131-160) - LS-C322856 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MARCKSL1 Antibody - LS-C334985 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of U2OS cell using MARCKSL1 antibody. Blue: DAPI for nuclear staining.

Anti-MARCKSL1 Antibody (aa132-160) - LS-C164036 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
MARCKSL1 Antibody western blot of 293 cell line lysates (35 ug/lane). The MARCKSL1 antibody detected the MARCKSL1 protein (arrow).

Anti-MARCKSL1 Antibody (C-Terminus) - LS-C151651 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MARCKSL1 / MRP antibody Western Blot of Human Fetal Lung. Antibody Dilution: 1.0 ug/ml. Antibody dilution: 1 ug/ml.

Anti-MARCKSL1 Antibody (clone 8C8) IHC-plus™ - LS-B6354 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 8C8
Anti-MARCKSL1 / MRP antibody IHC of human tonsil, germinal center. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6354 concentration 5 ug/ml.

Anti-MARCKSL1 Antibody (aa145-195) - LS-C289126 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human MARCKS-like 1 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-MARCKS-like 1 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.

MARCKS like protein Antibody (8C8) - H00065108-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 8C8
Western Blot: MARCKS like protein Antibody (8C8) [H00065108-M02] - Analysis of MARCKSL1 expression in transfected 293T cell line by MARCKSL1 monoclonal antibody (M02), clone 8C8.Lane 1: MARCKSL1 transfected lysate(19.398 KDa).Lane 2: Non-transfected lysate.

MARCKS like protein Antibody - NBP2-38160 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: MARCKS like protein Antibody [NBP2-38160] - Immunofluorescent staining of human cell line Hep G2 shows localization to cytosol.

MARCKS like protein Antibody - 32160002 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ELISA: MARCKS like protein Antibody [32160002]

MARCKS like protein Antibody (2H5) - H00065108-M03 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2H5

Monoclonal Anti-MARCKSL1 antibody produced in mouse - WH0065108M2 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 8C8
<B>Immunoblotting</B><BR/>Monoclonal Anti-MARCKSL1, <B>Cat. No. WH0065108M2</B> used at the antibody concentration: 1 μg/mL. Specific band of ~35.9 kDa using immunogen protein lysate.
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