MARCKSL1

Gene Symbol	MARCKSL1
Entrez Gene	65108
Alt Symbol	F52, MACMARCKS, MLP, MLP1, MRP
Species	Human
Gene Type	protein-coding
Description	MARCKS-like 1
Other Description	MARCKS-like protein 1|MARCKS-related protein|mac-MARCKS|macrophage myristoylated alanine-rich C kinase substrate
Swissprots	Q5TEE6 D3DPQ0 Q6NXS5 P49006
Accessions	AAP37955 EAX07537 EAX07538 EAX07539 P49006 AI879076 AL713653 CAD28462 AM393505 CAL38382 AY007131 BC007904 AAH07904 BC066915 AAH66915 DQ893237 ABM84163 DQ896567 ABM87566 DT218825 N70661 X70326 CAA49793 NM_023009 NP_075385 NR_052852
Function	Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May also affect cancer cell migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Associates with the membrane via the insertion of the N-terminal N-myristoyl chain and the partial insertion of the effector domain. Association of the effector domain with membranes may be regulated by Ca(2+)/calmodulin (By similarity). In prostate cancers, detected in the cytoplasm and associated with apical or basal membranes (By similarity). {ECO:0000250}.
Top Pathways	Fc gamma R-mediated phagocytosis, Leishmaniasis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MARCKS like protein full length protein - ab163921 from Abcam Category Protein Source Wheat germ Species Human

Human MARCKS like protein full length protein - ab156359 from Abcam Category Protein Source E. coli Species Human

Human MARCKS like protein protein fragment - ab163922 from Abcam Category Protein Source Wheat germ Species Human

MARCKSL1 Antibody Blocking Peptide - LS-E4474 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MARCKSL1 Antibody Blocking Peptide - LS-E23409 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MARCKS like protein Partial Recombinant Protein - H00065108-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

MARCKS like protein Recombinant Protein - H00065108-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 2 µg Species Human

Recombinant Human MARCKS like protein Protein - NBP2-23217 from Novus Biologicals Category Protein Prices $269.00 Sizes 20 µg Source E.coli Species Human

MARCKS like protein Peptide - P1092 from Novus Biologicals Category Peptide Species Human

MARCKS like protein Peptide - P1137 from Novus Biologicals Category Peptide Species Human

MARCKSL1-Antibody-C-term-Blocking-Peptide - BP16792b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MARCKS-like-1-Protein-MLP-Antibody-N-term-Blocking-peptide - BP2522a from Abgent, a WuXi AppTec company Category Protein Prices $80.00 Sizes 100 µg

MLP-Antibody-Center-Blocking-Peptide - BP2413b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human MARCKSL1 protein - orb191126 from Biorbyt Category Protein Prices $170.00, $289.00, $1,139.00 Sizes 2 μg, 10 μg, 100 μg Source E. coli Species Human

MARCKSL1 protein (His tag) - 80R-2746 from Fitzgerald Category Protein Prices $270.00 Sizes 20 µg Source E.coli

MARCKS-like 1 (His-tag) - AR50865PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 100 µg Source E. coli Species Human

MARCKS-like 1 (His-tag) - AR50865PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 20 µg Source E. coli Species Human

MARCKS-like 1 - H00065108-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MARCKS-like 1 - H00065108-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MARCKS-like 1 - H00065108-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MARCKS-like 1 - H00065108-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MARCKSL1, 1-195aa, Human, His tag, E.coli - 01-P2041 from ARP American Research Products Category Protein Prices $139.00, $369.00, $849.00 Sizes 5 µg, 20 µg, 100 µg Species Human

MARCKSL1 fusion protein - ag5274 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

MARCKSL1 fusion protein - ag1967 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human MARCKS-like 1, His-tagged - MARCKSL1-526H from Creative Biomart Category Protein Source E.coli Species Human

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