MARCKSL1

Gene Symbol MARCKSL1
Entrez Gene 65108
Alt Symbol F52, MACMARCKS, MLP, MLP1, MRP
Species Human
Gene Type protein-coding
Description MARCKS-like 1
Other Description MARCKS-like protein 1|MARCKS-related protein|mac-MARCKS|macrophage myristoylated alanine-rich C kinase substrate
Swissprots Q5TEE6 D3DPQ0 Q6NXS5 P49006
Accessions AAP37955 EAX07537 EAX07538 EAX07539 P49006 AI879076 AL713653 CAD28462 AM393505 CAL38382 AY007131 BC007904 AAH07904 BC066915 AAH66915 DQ893237 ABM84163 DQ896567 ABM87566 DT218825 N70661 X70326 CAA49793 NM_023009 NP_075385 NR_052852
Function Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May also affect cancer cell migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Associates with the membrane via the insertion of the N-terminal N-myristoyl chain and the partial insertion of the effector domain. Association of the effector domain with membranes may be regulated by Ca(2+)/calmodulin (By similarity). In prostate cancers, detected in the cytoplasm and associated with apical or basal membranes (By similarity). {ECO:0000250}.
Top Pathways Fc gamma R-mediated phagocytosis, Leishmaniasis

MARCKSL1 CRISPR/Cas9 KO Plasmid (h) - sc-403985 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCKSL1 HDR Plasmid (h) - sc-403985-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCKSL1 Double Nickase Plasmid (h) - sc-403985-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCKSL1 Double Nickase Plasmid (h2) - sc-403985-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCKSL1 CRISPR Activation Plasmid (h) - sc-403985-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCKSL1 CRISPR Activation Plasmid (h2) - sc-403985-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCKSL1 Lentiviral Activation Particles (h) - sc-403985-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCKSL1 Lentiviral Activation Particles (h2) - sc-403985-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCKSL1 siRNA (h) - sc-88464 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MARCKSL1 shRNA Plasmid (h) - sc-88464-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MARCKSL1 shRNA (h) Lentiviral Particles - sc-88464-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MARCKS like protein RNAi - H00065108-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU031701 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13040 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13040 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MARCKSL1 siRNA (Human) - CRJ2181 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MARCKSL1 (NM_023009.6) - SHH338331 from Creative biogene

Category siRNA
Species Reactivities Human

Human MARCKSL1 siRNA - orb272682 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MARCKSL1 shRNA Plasmid (Human) - CHJ2181 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MARCKSL1 miRNA 3'UTR clone - MiUTR3H-05430 from Creative biogene

Species Reactivities Human
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