Gene Symbol | SLC28A3 |
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Entrez Gene | 64078 |
Alt Symbol | CNT3 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 28 (concentrative nucleoside transporter), member 3 |
Other Description | concentrative Na(+)-nucleoside cotransporter 3|concentrative Na+-nucleoside cotransporter|solute carrier family 28 (sodium-coupled nucleoside transporter), member 3|solute carrier family 28 member 3 |
Swissprots | F5GYE3 B1AML0 B4E2S8 A8K9Y4 B2RA51 Q9HAS3 |
Accessions | EAW62686 Q9HAS3 AA643687 AF305210 AAG22551 AK022042 AK292849 BAF85538 AK304406 BAG65240 AK310861 AK314039 BAG36748 BC093821 AAH93821 BC093823 AAH93823 DB218604 DB237216 XM_011518905 XP_011517207 XM_011518906 XP_011517208 XM_011518907 XP_011517209 XM_011518908 XP_011517210 XM_011518909 XP_011517211 XM_011518910 XP_011517212 XR_929832 NM_001199633 NP_001186562 NM_022127 NP_071410 NR_037638 |
Function | Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides. Exhibits the transport characteristics of the nucleoside transport system cib or N3 subtype (N3/cib) (with marked transport of both thymidine and inosine). Employs a 2:1 sodium/nucleoside ratio. Also able to transport gemcitabine, 3'-azido-3'-deoxythymidine (AZT), ribavirin and 3-deazauridine. {ECO:0000269|PubMed:11032837, ECO:0000269|PubMed:16446384, ECO:0000269|PubMed:17140564}. |
Subcellular Location | Isoform 1: Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in pancreas, bone marrow, trachea, mammary gland, liver, prostate, and regions of intestine, brain, lung, placenta, testis, kidney, and heart. {ECO:0000269|PubMed:11032837}. |
CNT3 (C-15) - sc-48137 from Santa Cruz Biotechnology
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CNT3 (H-44) - sc-134529 from Santa Cruz Biotechnology
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SLC28A3 Antibody - NBP1-84418 from Novus Biologicals
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SLC28A3 Antibody - NBP2-29615 from Novus Biologicals
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SLC28A3 Antibody - NBP2-33301 from Novus Biologicals
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SLC28A3 Antibody - NBP1-84417 from Novus Biologicals
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Anti-SLC28A3 antibody produced in rabbit - HPA024729 from Sigma-Aldrich
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Anti-SLC28A3 antibody produced in rabbit - HPA023311 from Sigma-Aldrich
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SLC28A3 antibody - 18182-1-AP from Proteintech Group
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SLC28A3 / CNT3 antibody - TA337177 from Acris Antibodies
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Anti-SLC28A3 polyclonal antibody - CABT-BL139 from Creative Diagnostics
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Anti-SLC28A3 antibody - STJ112358 from St John's Laboratory Ltd
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SLC28A3 Antibody,Biotin conjugated - CSB-PA884504LD01HU from Cusabio
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SLC28A3 Antibody,FITC conjugated - CSB-PA884504LC01HU from Cusabio
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SLC28A3 Antibody,HRP conjugated - CSB-PA884504LB01HU from Cusabio
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SLC28A3 Antibody - CSB-PA884504LA01HU from Cusabio
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SLC28A3 antibody (Biotin) - orb46594 from Biorbyt
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SLC28A3 Polyclonal Antibody - CAC07750 from Biomatik
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Anti-SLC28A3 polyclonal antibody - CABT-BL3324 from Creative Diagnostics
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SLC28A3 - A10320 from NeoScientific
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SLC28A3 Polyclonal Antibody - A10320 from ABclonal
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Rabbit anti-SLC28A3 Antibody - 144-10320-50 from RayBiotech
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SLC28A3 Polyclonal Antibody - A10320 from ARP American Research Products
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SLC28A3 Antibody - middle region (ARP85220_P050) - ARP85220_P050 from Aviva Systems Biology
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Anti-SLC28A3 Antibody (Biotin) - LS-C501996 from LifeSpan Bioscience
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