NPLOC4

Gene Symbol	NPLOC4
Entrez Gene	55666
Alt Symbol	NPL4
Species	Human
Gene Type	protein-coding
Description	nuclear protein localization 4 homolog (S. cerevisiae)
Other Description	nuclear protein localization protein 4 homolog
Swissprots	Q8N3J1 Q9NWR5 Q9H8V2 Q8TAT6 Q9P229 Q9H964
Accessions	EAW89661 EAW89662 EAW89663 Q8TAT6 AB040932 BAA96023 AK000664 BAA91314 AK023046 BAB14372 AK023272 BAB14499 AK024398 AK074322 AK294473 BAG57700 AK311741 AL133629 AL834300 CAD38971 BC013406 BC025930 AAH25930 BU542911 CK903591 DA998574 DC322260 DQ587272 DQ587568 DQ895356 ABM86282 HY116973 HY179409 XM_011524979 XP_011523281 XM_011524980 XP_011523282 XM_011524981 XP_011523283 XM_011524982 XP_011523284 XR_934501 XR_934502 NM_017921 NP_060391 NR_130139 NR_130140
Function	The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm, cytosol {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}. Nucleus {ECO:0000250}. Note=Associated with the endoplasmic reticulum and nuclear. {ECO:0000250}.
Tissue Specificity	Expressed at highest levels in brain, heart, skeletal muscle, kidney and fetal liver. {ECO:0000269|PubMed:11574150}.
Top Pathways	Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Human NPL4 full length protein - ab153405 from Abcam Category Protein Source Wheat germ Species Human

Human NPL4 protein fragment - ab153406 from Abcam Category Protein Source Wheat germ Species Human

NPLOC4 Antibody Blocking Peptide - LS-E4964 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NPLOC4 Antibody Blocking Peptide - LS-E22765 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human NPLOC4 Protein - H00055666-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human NPLOC4 Protein - H00055666-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NPLOC4-Antibody-C-term-Blocking-Peptide - BP17356b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NPL4 - H00055666-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NPL4 - H00055666-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NPL4 - H00055666-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NPL4 - H00055666-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NPLOC4 fusion protein - Ag2219 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, T-HIS Species Human

Recombinant Human NPLOC4, His-tagged - NPLOC4-1345H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Nuclear protein localization protein 4 homolog(NPLOC4) - CSB-YP844706HU CSB-EP844706HU CSB-BP844706HU CSB-MP844706HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NPL4 - TP305829 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

NPLOC4 Recombinant Protein Antigen - NBP1-82166PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NPLOC4 Recombinant Protein Antigen - NBP1-82165PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NPLOC4 Peptide, Human - M34GP10557H from Creative Peptides Category Peptide Source Synthetic. Species Human

Nuclear protein localization protein 4 homolog (NPLOC4), Recombinant Protein - MBS1426818 from MyBioSource Category Protein Prices $1,400.00, $1,400.00, $1,630.00, $1,630.00, $2,360.00, $2,360.00, $2,805.00, $2,805.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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