Gene Symbol | MUC12 |
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Entrez Gene | 10071 |
Alt Symbol | MUC-11, MUC-12, MUC11 |
Species | Human |
Gene Type | protein-coding |
Description | mucin 12, cell surface associated |
Other Description | mucin 11|mucin-11|mucin-12 |
Swissprots | Q9UKN0 A6ND38 F5GWV9 Q9UKN1 |
Accessions | CCQ42956 EAW50190 Q9UKN1 AF147790 AAD55678 AF147791 AAD55679 AK024856 AK025404 AK296627 BAH12403 BC127877 AAI27878 NM_001164462 NP_001157934 |
Function | Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF- beta in intestinal epithelium. {ECO:0000269|PubMed:17058067}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Ubiquitous, with higher expression in colon. Down-regulated in colorectal cancer as well as in the colon of patients with ulcerative colitis (UC) and Crohn's disease (CD). {ECO:0000269|PubMed:10463611, ECO:0000269|PubMed:17058067}. |
Mucin 2 (Ccp58) - sc-7314 from Santa Cruz Biotechnology
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Mucin 5B (5B#19-2E) - sc-21768 from Santa Cruz Biotechnology
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Mucin 5B (4H310) - sc-71622 from Santa Cruz Biotechnology
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Mucin 12 (F-14) - sc-46396 from Santa Cruz Biotechnology
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Mucin 12 (P-18) - sc-46398 from Santa Cruz Biotechnology
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Mucin 12 (B-9) - sc-377269 from Santa Cruz Biotechnology
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Mucin 12 (G-1) - sc-377268 from Santa Cruz Biotechnology
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Mucin 12 (C-21) - sc-26372 from Santa Cruz Biotechnology
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Mucin 12 (H-300) - sc-66970 from Santa Cruz Biotechnology
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Anti-MUC12 antibody - ab121777 from Abcam
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Anti-MUC12 Antibody (aa10-24) - LS-C40616 from LifeSpan Bioscience
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Anti-MUC12 Antibody (aa541-555) - LS-C40617 from LifeSpan Bioscience
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Anti-MUC12 Antibody (aa601-650) - LS-C115953 from LifeSpan Bioscience
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MUC12 Antibody - NB200-124 from Novus Biologicals
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MUC12 Antibody - NB200-125 from Novus Biologicals
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MUC12 Antibody - NBP1-82607 from Novus Biologicals
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MUC12 Antibody - NBP1-59719 from Novus Biologicals
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MUC12 Antibody (8B10) - H00010071-M01-100ug from Novus Biologicals
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Anti-MUC12 antibody produced in rabbit - SAB2101532 from Sigma-Aldrich
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Monoclonal Anti-MUC12 antibody produced in mouse - SAB1412790 from Sigma-Aldrich
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Anti-MUC12 antibody produced in rabbit - HPA027769 from Sigma-Aldrich
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MUC12 antibody - middle region (ARP45581_P050) - ARP45581_P050 from Aviva Systems Biology
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MUC12 antibody - GTX30149 from GeneTex
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MUC12 antibody - GTX22298 from GeneTex
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MUC12 antibody - GTX23162 from GeneTex
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