TMIGD2

Gene Symbol TMIGD2
Entrez Gene 126259
Alt Symbol IGPR-1, IGPR1
Species Human
Gene Type protein-coding
Description transmembrane and immunoglobulin domain containing 2
Other Description CD28 homolog|immunoglobulin and proline-rich receptor 1|immunoglobulin-containing and proline-rich receptor 1|transmembrane and immunoglobulin domain-containing protein 2|transmembrane and immunoglobulin domain-containing protein 2 variant 2|transmembrane and immunoglobulin domain-containing protein 2 variant 3
Swissprots Q96BF3 Q6UW59
Accessions EAW69239 EAW69240 Q96BF3 AY358964 AAQ89323 BC015655 AAH15655 BU629751 HQ452865 AED88282 HQ452866 AED88283 HY260382 XM_011527679 XP_011525981 NM_001169126 NP_001162597 NM_001308232 NP_001295161 NM_144615 NP_653216
Function Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T- cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. {ECO:0000269|PubMed:22419821, ECO:0000269|PubMed:23784006}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:22419821}; Single-pass type I membrane protein {ECO:0000269|PubMed:22419821}.
Tissue Specificity Widely expressed, mainly by epithelial and endothelial cells, including bronchial epithelial cells of lung, breast glandular and lobular epithelia cells, urothelium of the bladder, skin epidermis, epithelium of gastrointestinal, rectum, endometrial glands of the uterus, ureter, fallopian tube epithelium, colonic epithelium, small bowl epithelium, stomach epithelium, including both chief and parietal cells, trophoblastic epithelium of placenta, and pancreatic acinar cells (at protein level). Consistently expressed in veins and arteries (at protein level). Not detected in thyroid, cerebellum, cerebral cortex and thymus (at protein level). Expressed in lymphoid organs, with highest levels in thymus, spleen, peripheral blood lymphocytes and liver. In the thymus, expressed in CD4+ and CD8+ single- and double-positive cells, but not in immature CD4- and CD8- double- negative cells (at protein level). In peripheral blood mononuclear cells, highly expressed on CD56+ or CD16+ natural killer cel

Anti-TMIGD2 antibody - ab121333 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TMIGD2 antibody (ab121333) at 1/250 dilutionLane 1 : Negative control (vector only transfected HEK293T lysate) Lane 2 : Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells

Anti-TMIGD2 antibody - ab180896 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-TMIGD2 antibody (ab180896) at 1 µg/ml + Mouse small intestine tissue lysate at 15 µg

Anti-TMIGD2 antibody - ab156392 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-TMIGD2 antibody (ab156392) at 1/100 dilution + NCI-H460 cell line lysate at 35 µg

Anti-TMIGD2 Antibody (aa119-147, AP) - LS-C271768 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TMIGD2 Antibody (aa119-147, APC) - LS-C271769 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TMIGD2 Antibody (aa119-147, Biotin) - LS-C271770 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TMIGD2 Antibody (aa119-147, FITC) - LS-C271771 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TMIGD2 Antibody (aa119-147, Azide-free, HRP) - LS-C271772 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TMIGD2 Antibody (aa119-147, PE) - LS-C271773 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TMIGD2 Antibody (aa119-147) - LS-C325807 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TMIGD2 Antibody (aa119-147) - LS-C156243 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
TMIGD2 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The TMIGD2 antibody detected the TMIGD2 protein (arrow).

Anti-TMIGD2 Antibody (C-Terminus) - LS-C201170 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of TMIGD2 in mouse small intestine tissue lysate with TMIGD2 antibody at 1 ug/ml.

TMIGD2 Antibody - NBP1-81164 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: TMIGD2 Antibody [NBP1-81164] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

TMIGD2 Antibody - H00126259-B01P from Novus Biologicals

Host Mouse
Clonality Polyclonal

Anti-TMIGD2 antibody produced in rabbit - SAB3501079 from Sigma-Aldrich

Prices $341.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>TMIGD2 Antibody: <B>Cat. No. SAB3501079</B>: Western blot analysis of TMIGD2 in Mouse small intestine tissue lysate with TMIGD2 antibody at 1 μg/mL.

ANTI-TMIGD2 (CENTER) antibody produced in rabbit - SAB1305321 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-TMIGD2 (Center): <B>Cat. No. SAB1305321</B>: TMIGD2 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35 μg/lane).

Anti-TMIGD2 antibody produced in rabbit - HPA011081 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TMIGD2: <B>Cat. No. HPA011081</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human gall bladder tissue showing membranous and/or cytoplasmic positivity in glandular cells.

TMIGD2-Antibody-Center - AP20167c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
TMIGD2 Antibody (Center) (Cat. #AP20167c) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the TMIGD2 antibody detected the TMIGD2 protein (arrow).

TMIGD2 Antibody - middle region (OAAB15553) - OAAB15553 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

TMIGD2 Antibody - abx031417 from Abbexa

Host Rabbit
Clonality Polyclonal

TMIGD2 antibody - H00126259-B01P from Acris Antibodies

Prices $360.00
Sizes 500 µg
Host Mouse
Clonality Polyclonal

TMIGD2 Antibody - 7617 from ProSci

Prices $79.00, $325.00
Sizes 20 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of TMIGD2 in mouse small intestine tissue lysate with TMIGD2 antibody at 1 μg/ml.

TMIGD2, Polyclonal Antibody - MBS6007345 from MyBioSource

Prices $550.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

TMIGD2, Polyclonal Antibody - MBS153433 from MyBioSource

Prices $140.00, $355.00
Sizes 20 µg, 100 µg
Host Rabbit
Clonality Polyclonal

TMIGD2 Antibody, Rabbit PAb - 13820-RP01-200 from Sino Biological

Prices $99.00, $99.00
Sizes 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal
Search more