TMIGD2

Gene Symbol TMIGD2
Entrez Gene 126259
Alt Symbol IGPR-1, IGPR1
Species Human
Gene Type protein-coding
Description transmembrane and immunoglobulin domain containing 2
Other Description CD28 homolog|immunoglobulin and proline-rich receptor 1|immunoglobulin-containing and proline-rich receptor 1|transmembrane and immunoglobulin domain-containing protein 2|transmembrane and immunoglobulin domain-containing protein 2 variant 2|transmembrane and immunoglobulin domain-containing protein 2 variant 3
Swissprots Q96BF3 Q6UW59
Accessions EAW69239 EAW69240 Q96BF3 AY358964 AAQ89323 BC015655 AAH15655 BU629751 HQ452865 AED88282 HQ452866 AED88283 HY260382 XM_011527679 XP_011525981 NM_001169126 NP_001162597 NM_001308232 NP_001295161 NM_144615 NP_653216
Function Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T- cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. {ECO:0000269|PubMed:22419821, ECO:0000269|PubMed:23784006}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:22419821}; Single-pass type I membrane protein {ECO:0000269|PubMed:22419821}.
Tissue Specificity Widely expressed, mainly by epithelial and endothelial cells, including bronchial epithelial cells of lung, breast glandular and lobular epithelia cells, urothelium of the bladder, skin epidermis, epithelium of gastrointestinal, rectum, endometrial glands of the uterus, ureter, fallopian tube epithelium, colonic epithelium, small bowl epithelium, stomach epithelium, including both chief and parietal cells, trophoblastic epithelium of placenta, and pancreatic acinar cells (at protein level). Consistently expressed in veins and arteries (at protein level). Not detected in thyroid, cerebellum, cerebral cortex and thymus (at protein level). Expressed in lymphoid organs, with highest levels in thymus, spleen, peripheral blood lymphocytes and liver. In the thymus, expressed in CD4+ and CD8+ single- and double-positive cells, but not in immature CD4- and CD8- double- negative cells (at protein level). In peripheral blood mononuclear cells, highly expressed on CD56+ or CD16+ natural killer cel

transmembrane and immunoglobulin domain containing 2, ELISA Kit - MBS9317683 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human TMIGD2 ELISA Kit - E039102 from Biobool

Category ELISA Kit

Human Transmembrane and immunoglobulin domain-containing protein 2 (TMIGD2) ELISA Kit - AE14158HU from ARP American Research Products

Category ELISA Kit
Prices $549.00
Sizes 96 t
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