FAM175A

Gene Symbol	FAM175A
Entrez Gene	84142
Alt Symbol	ABRA1, CCDC98
Species	Human
Gene Type	protein-coding
Description	family with sequence similarity 175, member A
Other Description	BRCA1-A complex subunit Abraxas|abraxas protein|coiled-coil domain containing 98|coiled-coil domain-containing protein 98
Swissprots	A5JJ07 Q9H8I1 Q9H9N4 Q6UWZ7
Accessions	EAX05941 EAX05942 EAX05943 Q6UWZ7 AK021582 AK022704 BAB14189 AK023676 BAB14635 AY358576 AAQ88939 BC016905 AAH16905 BC039573 AAH39573 BQ775930 DA765424 EF531340 ABP87396 XM_005263280 XP_005263337 XM_005263281 XP_005263338 XM_011532318 XP_011530620 NM_139076 NP_620775
Function	Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. {ECO:0000269|PubMed:17525340, ECO:0000269|PubMed:17643121, ECO:0000269|PubMed:17643122, ECO:0000269|PubMed:18077395, ECO:0000269|PubMed:19261748, ECO:0000269|PubMed:22357538}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:17525340, ECO:0000269|PubMed:17643121, ECO:0000269|PubMed:17643122}. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs).

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

BRCA1-A complex subunit Abraxas (FAM175A), Human, ELISA Kit - E01B0908 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

BRCA1 A complex subunit Abraxas (FAM175A), ELISA Kit - MBS7247785 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-A complex subunit Abraxas (FAM175A), ELISA Kit - MBS7236609 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-A complex subunit Abraxas (FAM175A), ELISA Kit - MBS7222531 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-A complex subunit Abraxas (FAM175A), ELISA Kit - MBS7210285 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-A complex subunit Abraxas (FAM175A), ELISA Kit - MBS7243587 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-A complex subunit Abraxas (FAM175A), ELISA Kit - MBS7216732 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-A complex subunit Abraxas (FAM175A), ELISA Kit - MBS7244934 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-A complex subunit Abraxas (FAM175A), ELISA Kit - MBS7238555 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-A complex subunit Abraxas (FAM175A), ELISA Kit - MBS7222940 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-A complex subunit Abraxas (FAM175A), ELISA Kit - MBS7238304 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-A complex subunit Abraxas (FAM175A), ELISA Kit - MBS7216567 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BRCA1-A complex subunit Abraxas (FAM175A), ELISA Kit - MBS7202763 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human FAM175A ELISA Kit - E005268 from Biobool Category ELISA Kit

anti-ABRA1 / CCDC98 antibody [ABRA1-01] - ARG62665 from Arigo Biolaboratories Category ELISA Kit

BRCA1-A complex subunit Abraxas, ELISA Kit - MBS285679 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Search more