Gene Symbol | CHSY3 |
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Entrez Gene | 337876 |
Alt Symbol | CHSY2, CSS3 |
Species | Human |
Gene Type | protein-coding |
Description | chondroitin sulfate synthase 3 |
Other Description | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3|N-acetylgalactosaminyltransferase 3|carbohydrate synthase 2|chSy-2|chondroitin glucuronyltransferase 3|chondroitin synthase 2|chondroitin synthase-2|glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II |
Swissprots | Q76L22 Q86Y52 B2RP97 Q70JA7 |
Accessions | EAW62379 Q70JA7 AB086062 BAC98832 AB175496 BAF47165 AJ504664 CAD43233 AJ578034 CAE17326 AJ632296 CAG17593 AJ862728 CAH89316 AY726604 BC137325 AAI37326 XM_005271982 XP_005272039 XM_005271983 XP_005272040 XM_011543363 XP_011541665 XM_011543364 XP_011541666 XM_011543365 XP_011541667 NM_175856 NP_787052 |
Function | Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Specific activity is much reduced compared to CHSY1. {ECO:0000269|PubMed:12907687}. |
Subcellular Location | Golgi apparatus, Golgi stack membrane {ECO:0000305|PubMed:12907687}; Single-pass type II membrane protein {ECO:0000305|PubMed:12907687}. |
Tissue Specificity | Detected at low levels in brain, cerebral cortex, uterus and small intestine. {ECO:0000269|PubMed:12907687}. |
Top Pathways | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate |
CHSY3 (C-17) - sc-50551 from Santa Cruz Biotechnology
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CHSY3 (D-20) - sc-50552 from Santa Cruz Biotechnology
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Anti-CHSY3 antibody - ab156217 from Abcam
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Anti-CHSY3 antibody - ab122874 from Abcam
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Anti-CHSY3 / CSS3 Antibody (aa531-560, APC) - LS-C233842 from LifeSpan Bioscience
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Anti-CHSY3 / CSS3 Antibody (aa531-560, AP) - LS-C233841 from LifeSpan Bioscience
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Anti-CHSY3 / CSS3 Antibody (aa531-560, Biotin) - LS-C233843 from LifeSpan Bioscience
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Anti-CHSY3 / CSS3 Antibody (aa531-560, FITC) - LS-C233844 from LifeSpan Bioscience
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Anti-CHSY3 / CSS3 Antibody (aa531-560, Azide-free, HRP) - LS-C249675 from LifeSpan Bioscience
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Anti-CHSY3 / CSS3 Antibody (aa531-560, PE) - LS-C233845 from LifeSpan Bioscience
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Anti-CHSY3 / CSS3 Antibody (aa531-560) - LS-C320388 from LifeSpan Bioscience
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Anti-CHSY3 / CSS3 Antibody (aa531-560) - LS-C157642 from LifeSpan Bioscience
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Anti-CHSY3 / CSS3 Antibody (aa107-156) - LS-C111225 from LifeSpan Bioscience
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Chondroitin sulfate synthase 3 Antibody - NBP1-85626 from Novus Biologicals
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Chondroitin sulfate synthase 3 Antibody - NBP1-59673 from Novus Biologicals
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Anti-CHSY3 antibody produced in rabbit - HPA044612 from Sigma-Aldrich
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Anti-CHSY-2, (N-terminal) antibody produced in rabbit - SAB2103730 from Sigma-Aldrich
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ANTI-CHSY3 (CENTER) antibody produced in rabbit - SAB1305311 from Sigma-Aldrich
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CHSY-2 antibody - N-terminal region (ARP49126_P050) - ARP49126_P050 from Aviva Systems Biology
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CHSY3-Antibody-Center - AP20033c from Abgent, a WuXi AppTec company
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CHSY3-Antibody-Center - AP21080a from Abgent, a WuXi AppTec company
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CHSY3 Antibody - middle region (OAAB15441) - OAAB15441 from Aviva Systems Biology
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CHSY2 antibody - 70R-6580 from Fitzgerald
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Anti -CHSY3, ID (CHSY3, CHSY2, CSS3, Chondroitin sulfate synthase 3, Carbohydrate synthase2, Chondroitin glucuronyltransferase 3, Chondroitin synthase 2,Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferaseII, N-acetylgala - 033891 from USBiological Life Science
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Anti -CHSY3, ID (CHSY3, CHSY2, CSS3, Chondroitin sulfate synthase 3, Carbohydrate synthase2, Chondroitin glucuronyltransferase 3, Chondroitin synthase 2,Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferaseII, N-acetylgala - 033891-AP from USBiological Life Science
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