TRIP6

Gene Symbol TRIP6
Entrez Gene 7205
Alt Symbol OIP-1, OIP1, TRIP-6, TRIP6i2, ZRP-1
Species Human
Gene Type protein-coding
Description thyroid hormone receptor interactor 6
Other Description OPA-interacting protein 1|TR-interacting protein 6|thyroid hormone receptor interacting protein 6|thyroid receptor-interacting protein 6|zyxin related protein 1
Swissprots F2ZC08 O15275 Q9BUE5 A4D2E7 Q9UNT4 Q9BTB2 Q15654 F2ZC07 O15170 Q9BXP3
Accessions AAD03037 AAK21007 EAL23817 EAW76471 EAW76472 EAW76473 EAW76474 Q15654 AB628085 BAK20496 AB628086 BAK20497 AB628087 BAK20498 AB628088 BAK20499 AF000974 AAB62222 AF025437 AAC39557 AJ001902 CAA05080 AK056773 AK291906 BAF84595 AK309312 BC002680 AAH02680 BC004249 AAH04249 BC004999 AAH04999 BC021540 AAH21540 BC028985 AAH28985 BM800083 CR749505 CAH18326 DQ892893 ABM83819 DQ896140 ABM87139 L40374 AAC41740 XM_011516545 XP_011514847 NM_003302 NP_003293
Function Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor. {ECO:0000269|PubMed:14688263, ECO:0000269|PubMed:15489293, ECO:0000269|PubMed:16624523, ECO:0000269|PubMed:19017743}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000269|PubMed:16624523}. Cell junction, focal adhesion {ECO:0000269|PubMed:16624523}. Nucleus {ECO:0000269|PubMed:16624523}. Cytoplasm {ECO:0000269|PubMed:16624523}. Note=Shuttles between nucleus and cytoplasm.
Tissue Specificity Abundantly expressed in kidney, liver and lung. Lower levels in heart, placenta and pancreas. Expressed in colonic epithelial cells. Up-regulated in colonic tumors. {ECO:0000269|PubMed:19017743}.
Top Pathways NOD-like receptor signaling pathway

TRIP6 (C-5) - sc-166330 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TRIP6 (C-5): sc-166330. Western blot analysis of TRIP6 expression in non-transfected: sc-117752 (A) and human TRIP6 transfected: sc-114028 (B) 293T whole cell lysates.

TRIP6 (F-5) - sc-365122 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TRIP6 (F-5): sc-365122. Western blot analysis of TRIP6 expression in HeLa (A) and K-562 (B) whole cell lysates.

TRIP6 (D-11) - sc-166311 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TRIP6 (D-11): sc-166311. Western blot analysis of TRIP6 expression in non-transfected: sc-117752 (A) and human TRIP6 transfected: sc-114028 (B) 293T whole cell lysates.

TRIP6 (G-5) - sc-376550 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TRIP6 (G-5): sc-376550. Immunoperoxidase staining of formalin fixed, paraffin-embedded human uterine cervix tissue showing cytoplasmic and nuclear staining of squamous epithelial cells.

TRIP6 (F-10) - sc-365972 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TRIP6 (F-10): sc-365972. Western blot analysis of TRIP6 expression in K-562 whole cell lysate.

TRIP6 (S-20) - sc-34981 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TRIP6 (S-20): sc-34981. Western blot analysis of TRIP6 expression in non-transfected: sc-117752 (A) and human TRIP6 transfected: sc-114028 (B) 293T whole cell lysates.

TRIP6 (N-20) - sc-34979 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TRIP6 (N-20): sc-34979. Western blot analysis of TRIP6 expression in K-562 whole cell lysate.

TRIP6 (P-20) - sc-34980 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TRIP6 (P-20): sc-34980. Western blot analysis of TRIP6 expression in non-transfected: sc-117752 (A) and human TRIP6 transfected: sc-114028 (B) 293T whole cell lysate.

TRIP6 (M-87) - sc-292304 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TRIP6 (M-87): sc-292304. Western blot analysis of TRIP6 expression in non-transfected: sc-117752 (A) and human TRIP6 transfected: sc-114028 (B) 293T whole cell lysates.

TRIP6 (H-95) - sc-292303 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-TRIP6 antibody - ab137478 from Abcam

Prices $384.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-TRIP6 antibody (ab137478) at 1/500 dilution + A. Hela whole cell lysate/extract at 30 µg

Anti-TRIP6 antibody - ab58373 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-TRIP6 antibody - ab70747 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TRIP6 antibody (ab70747) at 0.04 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-TRIP6 antibody - ab12329 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-TRIP6 antibody - ab12330 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIP6 antibody - ab123094 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-TRIP6 antibody (ab123094) at 1/100 dilution + HepG2 cell line lysates at 35 µg

Anti-TRIP6 antibody - ab99488 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-TRIP6 antibody (ab99488) at 2 µg/ml + K562 lysate at 35 µgdeveloped using the ECL technique

Anti-TRIP6 antibody [6H4] - ab140672 from Abcam

Host Mouse
Clonality Monoclonal
Clone 6H4
Flow cytometric analysis of K562 cells labelling TRIP6 with ab140672 at 1/200 dilution (green); negative control (red).

Anti-ZRP-1 / TRIP6 Antibody (Internal) - LS-C144321 from LifeSpan Bioscience

Prices $345.00, $1,035.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry of TRIP6 in HeLa cells with TRIP6 antibody.

Anti-ZRP-1 / TRIP6 Antibody (aa1-50) - LS-C89732 from LifeSpan Bioscience

Prices $545.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-ZRP-1 / TRIP6 Antibody (aa51-149) - LS-C132674 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ZRP-1 / TRIP6 Antibody (aa95-124, APC) - LS-C242179 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZRP-1 / TRIP6 Antibody (aa95-124, AP) - LS-C242180 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZRP-1 / TRIP6 Antibody (aa95-124, Biotin) - LS-C242181 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZRP-1 / TRIP6 Antibody (aa95-124, FITC) - LS-C242182 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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