TRIP6

Gene Symbol TRIP6
Entrez Gene 7205
Alt Symbol OIP-1, OIP1, TRIP-6, TRIP6i2, ZRP-1
Species Human
Gene Type protein-coding
Description thyroid hormone receptor interactor 6
Other Description OPA-interacting protein 1|TR-interacting protein 6|thyroid hormone receptor interacting protein 6|thyroid receptor-interacting protein 6|zyxin related protein 1
Swissprots F2ZC08 O15275 Q9BUE5 A4D2E7 Q9UNT4 Q9BTB2 Q15654 F2ZC07 O15170 Q9BXP3
Accessions AAD03037 AAK21007 EAL23817 EAW76471 EAW76472 EAW76473 EAW76474 Q15654 AB628085 BAK20496 AB628086 BAK20497 AB628087 BAK20498 AB628088 BAK20499 AF000974 AAB62222 AF025437 AAC39557 AJ001902 CAA05080 AK056773 AK291906 BAF84595 AK309312 BC002680 AAH02680 BC004249 AAH04249 BC004999 AAH04999 BC021540 AAH21540 BC028985 AAH28985 BM800083 CR749505 CAH18326 DQ892893 ABM83819 DQ896140 ABM87139 L40374 AAC41740 XM_011516545 XP_011514847 NM_003302 NP_003293
Function Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor. {ECO:0000269|PubMed:14688263, ECO:0000269|PubMed:15489293, ECO:0000269|PubMed:16624523, ECO:0000269|PubMed:19017743}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000269|PubMed:16624523}. Cell junction, focal adhesion {ECO:0000269|PubMed:16624523}. Nucleus {ECO:0000269|PubMed:16624523}. Cytoplasm {ECO:0000269|PubMed:16624523}. Note=Shuttles between nucleus and cytoplasm.
Tissue Specificity Abundantly expressed in kidney, liver and lung. Lower levels in heart, placenta and pancreas. Expressed in colonic epithelial cells. Up-regulated in colonic tumors. {ECO:0000269|PubMed:19017743}.
Top Pathways NOD-like receptor signaling pathway

TRIP6 CRISPR/Cas9 KO Plasmid (h) - sc-407019 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIP6 HDR Plasmid (h) - sc-407019-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIP6 Double Nickase Plasmid (h) - sc-407019-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIP6 Double Nickase Plasmid (h2) - sc-407019-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIP6 CRISPR Activation Plasmid (h) - sc-407019-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIP6 CRISPR Activation Plasmid (h2) - sc-407019-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIP6 Lentiviral Activation Particles (h) - sc-407019-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIP6 Lentiviral Activation Particles (h2) - sc-407019-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIP6 siRNA (h) - sc-45561 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRIP6 shRNA Plasmid (h) - sc-45561-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRIP6 shRNA (h) Lentiviral Particles - sc-45561-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRIP6 RNAi - H00007205-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU017441 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN22032 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22032 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TRIP6 siRNA (Human) - CRH4943 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TRIP6 - MBS8233981 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TRIP6 (NM_003302.2) - SHH435236 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human TRIP6(NM_003302.2) - SHL095880 from Creative biogene

Category siRNA
Species Reactivities Human

TRIP6 shRNA Plasmid (Human) - CHH4943 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TRIP6 miRNA 3'UTR clone - MiUTR1H-10772 from Creative biogene

Species Reactivities Human
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