TRIP6

Gene Symbol	TRIP6
Entrez Gene	7205
Alt Symbol	OIP-1, OIP1, TRIP-6, TRIP6i2, ZRP-1
Species	Human
Gene Type	protein-coding
Description	thyroid hormone receptor interactor 6
Other Description	OPA-interacting protein 1|TR-interacting protein 6|thyroid hormone receptor interacting protein 6|thyroid receptor-interacting protein 6|zyxin related protein 1
Swissprots	F2ZC08 O15275 Q9BUE5 A4D2E7 Q9UNT4 Q9BTB2 Q15654 F2ZC07 O15170 Q9BXP3
Accessions	AAD03037 AAK21007 EAL23817 EAW76471 EAW76472 EAW76473 EAW76474 Q15654 AB628085 BAK20496 AB628086 BAK20497 AB628087 BAK20498 AB628088 BAK20499 AF000974 AAB62222 AF025437 AAC39557 AJ001902 CAA05080 AK056773 AK291906 BAF84595 AK309312 BC002680 AAH02680 BC004249 AAH04249 BC004999 AAH04999 BC021540 AAH21540 BC028985 AAH28985 BM800083 CR749505 CAH18326 DQ892893 ABM83819 DQ896140 ABM87139 L40374 AAC41740 XM_011516545 XP_011514847 NM_003302 NP_003293
Function	Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor. {ECO:0000269|PubMed:14688263, ECO:0000269|PubMed:15489293, ECO:0000269|PubMed:16624523, ECO:0000269|PubMed:19017743}.
Subcellular Location	Cytoplasm, cytoskeleton {ECO:0000269|PubMed:16624523}. Cell junction, focal adhesion {ECO:0000269|PubMed:16624523}. Nucleus {ECO:0000269|PubMed:16624523}. Cytoplasm {ECO:0000269|PubMed:16624523}. Note=Shuttles between nucleus and cytoplasm.
Tissue Specificity	Abundantly expressed in kidney, liver and lung. Lower levels in heart, placenta and pancreas. Expressed in colonic epithelial cells. Up-regulated in colonic tumors. {ECO:0000269|PubMed:19017743}.
Top Pathways	NOD-like receptor signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TRIP6 full length protein - ab132099 from Abcam Category Protein Source Wheat germ Species Human

Human TRIP6 protein fragment - ab159749 from Abcam Category Protein Source Wheat germ Species Human

Human TRIP6 protein fragment - ab159750 from Abcam Category Protein Source Wheat germ Species Human

ZRP-1 / TRIP6 Antibody Blocking Peptide - LS-E3064 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ZRP-1 / TRIP6 Antibody Blocking Peptide - LS-E18507 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ZRP-1 / TRIP6 Antibody Blocking Peptide - LS-E18508 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ZRP-1 / TRIP6 Antibody Blocking Peptide - LS-E27324 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ZRP-1 / TRIP6 Antibody Blocking Peptide - LS-E31012 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human TRIP6 Protein - H00007205-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TRIP6 Partial Recombinant Protein - H00007205-Q02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human TRIP6 Protein - H00007205-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TRIP6 Blocking Peptide - NBP1-76305PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

TRIP6-Antibody-N-term-Blocking-Peptide - BP14201a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TRIP6 blocking peptide - GTX88170-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Bovine

TRIP6 Protein Lysate (APL10543) - APL10543 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

TRIP6 Protein Lysate (APL10544) - APL10544 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

TRIP6 Blocking Peptide - 33R-6433 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TRIP6 Blocking Peptide - 33R-1536 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TRIP6 Peptide - AC21-2146-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

TRIP6 / OIP1 - H00007205-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TRIP6 / OIP1 - H00007205-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TRIP6 / OIP1 - H00007205-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TRIP6 / OIP1 - H00007205-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TRIP6 / OIP1 - H00007205-Q02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

TRIP6 / OIP1 - H00007205-Q02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

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