Gene Symbol | ICT1 |
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Entrez Gene | 3396 |
Alt Symbol | DS-1, DS1, MRP-L58 |
Species | Human |
Gene Type | protein-coding |
Description | immature colon carcinoma transcript 1 |
Other Description | 39S ribosomal protein L58, mitochondrial|digestion substraction 1|immature colon carcinoma transcript 1 protein|peptidyl-tRNA hydrolase ICT1, mitochondrial |
Swissprots | Q53HM7 Q53Y11 B2RAD1 Q14197 |
Accessions | EAW89227 Q14197 AK222553 BAD96273 AK314138 BAG36828 BC015335 AAH15335 BI870683 BT007111 AAP35775 DB456649 DQ890655 ABM81581 DQ893834 ABM84760 X81788 CAA57387 NM_001303265 NP_001290194 NM_001545 NP_001536 |
Function | Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes. {ECO:0000269|PubMed:20186120}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:20186120, ECO:0000269|PubMed:23908630}. |
Tissue Specificity | Down-regulated during the in vitro differentiation of HT29-D4 colon carcinoma cells. {ECO:0000269|PubMed:8575443}. |
ICT1 (T-14) - sc-164630 from Santa Cruz Biotechnology
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ICT1 (2A8) - sc-100658 from Santa Cruz Biotechnology
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Anti-ICT1 antibody - ab168437 from Abcam
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Anti-ICT1 antibody - ab55259 from Abcam
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Anti-ICT1 antibody [AT1E9] - ab177528 from Abcam
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Anti-ICT1 antibody - C-terminal - ab180210 from Abcam
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Anti-ICT1 / DS1 Antibody (aa108-157) - LS-C111571 from LifeSpan Bioscience
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Anti-ICT1 / DS1 Antibody (clone 6F8) - LS-C197482 from LifeSpan Bioscience
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Anti-ICT1 / DS1 Antibody - LS-C310682 from LifeSpan Bioscience
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Anti-ICT1 / DS1 Antibody - LS-C308369 from LifeSpan Bioscience
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Anti-ICT1 / DS1 Antibody (FITC) - LS-C318313 from LifeSpan Bioscience
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Anti-ICT1 / DS1 Antibody (Biotin) - LS-C318314 from LifeSpan Bioscience
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Anti-ICT1 / DS1 Antibody (HRP) - LS-C318316 from LifeSpan Bioscience
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Anti-ICT1 / DS1 Antibody (clone AT1E9) - LS-C200846 from LifeSpan Bioscience
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Anti-ICT1 / DS1 Antibody (aa107-207, Azide-free) - LS-C327597 from LifeSpan Bioscience
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Anti-ICT1 / DS1 Antibody - LS-C319056 from LifeSpan Bioscience
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Anti-ICT1 / DS1 Antibody (aa153-179) - LS-C203980 from LifeSpan Bioscience
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Anti-ICT1 / DS1 Antibody (clone 2F9) - LS-C337999 from LifeSpan Bioscience
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ICT Antibody - NBP1-87963 from Novus Biologicals
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ICT Antibody - NBP1-55014 from Novus Biologicals
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ICT Antibody - H00003396-B01P from Novus Biologicals
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ICT Antibody - H00003396-D01P from Novus Biologicals
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ICT Antibody - H00003396-A01 from Novus Biologicals
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ICT Antibody (4C10) - H00003396-M06 from Novus Biologicals
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ICT Antibody (6F8) - H00003396-M05 from Novus Biologicals
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