Gene Symbol | STXBP5 |
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Entrez Gene | 134957 |
Alt Symbol | LGL3, LLGL3, Nbla04300 |
Species | Human |
Gene Type | protein-coding |
Description | syntaxin binding protein 5 (tomosyn) |
Other Description | lethal(2) giant larvae protein homolog 3|putative protein product of Nbla04300|syntaxin-binding protein 5|tomosyn|tomosyn-1 |
Swissprots | Q5T5C1 Q14DF3 Q5T5C0 Q96NG9 Q8NBG8 Q5T5C2 |
Accessions | EAW47819 EAW47820 EAW47821 EAW47822 EAW47823 Q5T5C0 AB073398 BAE45727 AI079651 AK055484 BAB70930 AK090549 BAC03475 AK128121 BAG54632 AL834152 AW020148 BC043173 BC043645 BC065713 BC107737 AAI07738 BC113382 AAI13383 BC113408 AAI13409 CB140025 HG499775 XM_006715339 XP_006715402 XM_011535449 XP_011533751 XM_011535450 XP_011533752 XM_011535451 XP_011533753 XM_011535452 XP_011533754 XM_011535453 XP_011533755 XM_011535454 XP_011533756 XR_245502 XR_245504 XR_942280 XR_942282 XR_942284 XR_942285 NM_001127715 NP_001121187 NM_139244 NP_640337 |
Function | Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release. Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane. Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane. Competes with STXBP1 for STX1 binding (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Cytoplasmic, and associated with vesicular membranes and the plasma membrane. Detected at synapses and on synaptic vesicles (By similarity). {ECO:0000250}. |
Tomosyn (H-55) - sc-98350 from Santa Cruz Biotechnology
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Tomosyn (L-18) - sc-79287 from Santa Cruz Biotechnology
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Tomosyn (P-16) - sc-79288 from Santa Cruz Biotechnology
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Tomosyn (15) - sc-136105 from Santa Cruz Biotechnology
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Anti-Tomosyn antibody - ab41271 from Abcam
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Anti-Tomosyn antibody - ab45228 from Abcam
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Anti-Tomosyn antibody - ab101998 from Abcam
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Tomosyn Antibody - NBP1-89583 from Novus Biologicals
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Tomosyn Antibody - NB100-91307 from Novus Biologicals
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Tomosyn Antibody - NBP2-20683 from Novus Biologicals
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Tomosyn Antibody - H00134957-A01 from Novus Biologicals
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Tomosyn/STXBP5 Polyclonal Antibody - bs-12126R from Bioss
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Rabbit Anti-Tomosyn/STXBP5 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12126R-A350 from Bioss
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Rabbit Anti-Tomosyn/STXBP5 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12126R-A488 from Bioss
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Rabbit Anti-Tomosyn/STXBP5 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-12126R-A555 from Bioss
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Rabbit Anti-Tomosyn/STXBP5 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-12126R-A647 from Bioss
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Rabbit Anti-Tomosyn/STXBP5 Polyclonal Antibody, Cy3 Conjugated - bs-12126R-Cy3 from Bioss
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Rabbit Anti-Tomosyn/STXBP5 Polyclonal Antibody, Cy5 Conjugated - bs-12126R-Cy5 from Bioss
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Rabbit Anti-Tomosyn/STXBP5 Polyclonal Antibody, Cy5.5 Conjugated - bs-12126R-Cy5.5 from Bioss
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Rabbit Anti-Tomosyn/STXBP5 Polyclonal Antibody, Cy7 Conjugated - bs-12126R-Cy7 from Bioss
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Rabbit Anti-Tomosyn/STXBP5 Polyclonal Antibody, FITC Conjugated - bs-12126R-FITC from Bioss
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Rabbit Anti-Tomosyn/STXBP5 Polyclonal Antibody, Biotin Conjugated - bs-12126R-Biotin from Bioss
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Rabbit Anti-Tomosyn/STXBP5 Polyclonal Antibody, HRP Conjugated - bs-12126R-HRP from Bioss
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Anti-STXBP5 antibody produced in rabbit - HPA039991 from Sigma-Aldrich
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Anti-STXBP5 (N-terminal) antibody produced in rabbit - SAB2700571 from Sigma-Aldrich
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