STXBP5

Gene Symbol	STXBP5
Entrez Gene	134957
Alt Symbol	LGL3, LLGL3, Nbla04300
Species	Human
Gene Type	protein-coding
Description	syntaxin binding protein 5 (tomosyn)
Other Description	lethal(2) giant larvae protein homolog 3|putative protein product of Nbla04300|syntaxin-binding protein 5|tomosyn|tomosyn-1
Swissprots	Q5T5C1 Q14DF3 Q5T5C0 Q96NG9 Q8NBG8 Q5T5C2
Accessions	EAW47819 EAW47820 EAW47821 EAW47822 EAW47823 Q5T5C0 AB073398 BAE45727 AI079651 AK055484 BAB70930 AK090549 BAC03475 AK128121 BAG54632 AL834152 AW020148 BC043173 BC043645 BC065713 BC107737 AAI07738 BC113382 AAI13383 BC113408 AAI13409 CB140025 HG499775 XM_006715339 XP_006715402 XM_011535449 XP_011533751 XM_011535450 XP_011533752 XM_011535451 XP_011533753 XM_011535452 XP_011533754 XM_011535453 XP_011533755 XM_011535454 XP_011533756 XR_245502 XR_245504 XR_942280 XR_942282 XR_942284 XR_942285 NM_001127715 NP_001121187 NM_139244 NP_640337
Function	Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release. Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane. Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane. Competes with STXBP1 for STX1 binding (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Cytoplasmic, and associated with vesicular membranes and the plasma membrane. Detected at synapses and on synaptic vesicles (By similarity). {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Tomosyn peptide - ab45226 from Abcam Category Peptide

Human Tomosyn peptide - ab45227 from Abcam Category Peptide

Human Tomosyn protein fragment - ab165387 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human Tomosyn Protein - H00134957-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

STXBP5-Antibody-Center-Blocking-Peptide - BP17209c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

STXBP5 - H00134957-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

STXBP5 - H00134957-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

STXBP5 fusion protein - ag21629 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Syntaxin-binding protein 5(STXBP5) ,partial - CSB-YP722568HU CSB-EP722568HU CSB-BP722568HU CSB-MP722568HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Tomosyn Protein - NBP1-89583PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

STXBP5 Peptide, Human - M34GP15371H from Creative Peptides Category Peptide Source Synthetic. Species Human

Syntaxin-binding protein 5 (STXBP5), partial, Recombinant Protein - MBS1465213 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Tomosyn Recombinant Protein Antigen - NBP2-56176PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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