Gene Symbol | TRIM40 |
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Entrez Gene | 135644 |
Alt Symbol | RNF35 |
Species | Human |
Gene Type | protein-coding |
Description | tripartite motif containing 40 |
Other Description | RING finger protein 35|probable E3 NEDD8-protein ligase|ring finger RNF35|tripartite motif-containing protein 40 |
Swissprots | Q8TD96 Q5SS36 Q5SRJ6 Q6P9F5 |
Accessions | BAD13705 BAD13706 BAE78604 EAX03265 EAX03266 Q6P9F5 AF489517 AAM09503 BC060785 AAH60785 CB990357 EU446570 ABZ92099 XM_011514305 XP_011512607 XM_011514306 XP_011512608 XM_011514307 XP_011512609 XM_011514308 XP_011512610 XM_011514309 XP_011512611 XM_011547189 XP_011545491 XM_011547190 XP_011545492 XM_011547191 XP_011545493 XM_011547192 XP_011545494 XM_011547604 XP_011545906 XM_011547842 XP_011546144 XM_011547843 XP_011546145 XM_011548011 XP_011546313 XM_011548012 XP_011546314 XM_011548013 XP_011546315 XM_011548199 XP_011546501 XM_011548200 XP_011546502 XM_011548201 XP_011546503 XM_011548202 XP_011546504 XM_011548384 XP_011546686 XM_011548385 XP_011546687 XM_011548386 XP_011546688 NM_001286633 NP_001273562 NM_138700 NP_619645 |
Function | May function as an E3 ubiquitin-protein ligase of the NEDD8 conjugation pathway. Promotes neddylation of IKBKG/NEMO, stabilizing NFKBIA, and inhibiting of NF-kappaB nuclear translocation and activity. {ECO:0000269|PubMed:21474709}. |
Tissue Specificity | Highly expressed in normal gastrointestinal epithelia but that is down-regulated in gastrointestinal carcinomas and chronic inflammatory lesions of the gastrointestinal tract. {ECO:0000269|PubMed:21474709}. |
TRIM40 (D-20) - sc-249080 from Santa Cruz Biotechnology
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TRIM40 (S-16) - sc-249078 from Santa Cruz Biotechnology
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Anti-RNF35 antibody - ab200354 from Abcam
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Anti-RNF35 antibody - ab88109 from Abcam
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Anti-RNF35 antibody - ab4367 from Abcam
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Anti-RNF35 antibody [EPR9668] - ab156583 from Abcam
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Anti-TRIM40 Antibody (C-Terminus) - LS-C345379 from LifeSpan Bioscience
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Anti-TRIM40 Antibody (aa246-258) - LS-C55409 from LifeSpan Bioscience
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TRIM40 Antibody - H00135644-B01P from Novus Biologicals
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TRIM40 Antibody - H00135644-B01 from Novus Biologicals
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TRIM40 Antibody - NBP1-92530 from Novus Biologicals
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Anti-TRIM40 (C-terminal) antibody produced in goat - SAB2501853 from Sigma-Aldrich
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Anti-TRIM40 antibody produced in rabbit - HPA043818 from Sigma-Aldrich
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Anti-TRIM40 antibody produced in mouse - SAB1400800 from Sigma-Aldrich
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TRI40 Antibody - C-terminal region (ARP34863_P050) - ARP34863_P050 from Aviva Systems Biology
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RNF35--TRIM40-Antibody-C-Term - AF2321a from Abgent, a WuXi AppTec company
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Goat Anti-RNF35 / TRIM40 Antibody (OAEB00349) - OAEB00349 from Aviva Systems Biology
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TRIM40 / RNF35 antibody - H00135644-B01 from Acris Antibodies
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TRIM40 / RNF35 antibody - H00135644-B01P from Acris Antibodies
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Anti-RNF35 Antibody - AC21-0345 from Abcore
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Anti-RNF35 Antibody (AMCA) - AC21-0345-01 from Abcore
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Anti-RNF35 Antibody (AP) - AC21-0345-02 from Abcore
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Anti-RNF35 Antibody (APC) - AC21-0345-03 from Abcore
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Anti-RNF35 Antibody (APC-Cy5.5) - AC21-0345-04 from Abcore
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Anti-RNF35 Antibody (APC-Cy7) - AC21-0345-05 from Abcore
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