Gene Symbol | TRIM40 |
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Entrez Gene | 135644 |
Alt Symbol | RNF35 |
Species | Human |
Gene Type | protein-coding |
Description | tripartite motif containing 40 |
Other Description | RING finger protein 35|probable E3 NEDD8-protein ligase|ring finger RNF35|tripartite motif-containing protein 40 |
Swissprots | Q8TD96 Q5SS36 Q5SRJ6 Q6P9F5 |
Accessions | BAD13705 BAD13706 BAE78604 EAX03265 EAX03266 Q6P9F5 AF489517 AAM09503 BC060785 AAH60785 CB990357 EU446570 ABZ92099 XM_011514305 XP_011512607 XM_011514306 XP_011512608 XM_011514307 XP_011512609 XM_011514308 XP_011512610 XM_011514309 XP_011512611 XM_011547189 XP_011545491 XM_011547190 XP_011545492 XM_011547191 XP_011545493 XM_011547192 XP_011545494 XM_011547604 XP_011545906 XM_011547842 XP_011546144 XM_011547843 XP_011546145 XM_011548011 XP_011546313 XM_011548012 XP_011546314 XM_011548013 XP_011546315 XM_011548199 XP_011546501 XM_011548200 XP_011546502 XM_011548201 XP_011546503 XM_011548202 XP_011546504 XM_011548384 XP_011546686 XM_011548385 XP_011546687 XM_011548386 XP_011546688 NM_001286633 NP_001273562 NM_138700 NP_619645 |
Function | May function as an E3 ubiquitin-protein ligase of the NEDD8 conjugation pathway. Promotes neddylation of IKBKG/NEMO, stabilizing NFKBIA, and inhibiting of NF-kappaB nuclear translocation and activity. {ECO:0000269|PubMed:21474709}. |
Tissue Specificity | Highly expressed in normal gastrointestinal epithelia but that is down-regulated in gastrointestinal carcinomas and chronic inflammatory lesions of the gastrointestinal tract. {ECO:0000269|PubMed:21474709}. |
Human RNF35 full length protein - ab165391 from Abcam
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Human RNF35 peptide - ab23027 from Abcam
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TRIM40 Antibody Blocking Peptide - LS-E25517 from LifeSpan Bioscience
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Recombinant Human TRIM40 Protein - H00135644-P01 from Novus Biologicals
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RNF35 blocking peptide - GTX89816-PEP from GeneTex
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RNF35 Peptide - AC21-0345-P from Abcore
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TRIM40 / RNF35 - H00135644-P01-10 from Acris Antibodies
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TRIM40 / RNF35 - H00135644-P01-25 from Acris Antibodies
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RNF35 Peptide - 46-310P from ProSci
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Recombinant Human Tripartite motif-containing protein 40(TRIM40) - CSB-YP764755HU CSB-EP764755HU CSB-BP764755HU CSB-MP764755HU from Cusabio
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RNF35/TRIM40, Peptide - MBS425172 from MyBioSource
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TRIM40 Protein - NBP1-92530PEP from Novus Biologicals
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TRIM40 Peptide, Human - M34GP16594H from Creative Peptides
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TRIM40 Immunizing peptide - orb16376 from Biorbyt
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