MLX

Gene Symbol MLX
Entrez Gene 6945
Alt Symbol MAD7, MXD7, TCFL4, bHLHd13
Species Human
Gene Type protein-coding
Description MLX, MAX dimerization protein
Other Description BigMax protein|MAX-like bHLHZIP protein|class D basic helix-loop-helix protein 13|max-like protein X|transcription factor-like protein 4
Swissprots Q9H2V1 Q53XM6 Q9H2V2 B2RD73 B2RAV8 Q9H2V0 Q96FL2 Q9NXN3 Q9UH92 A8K2J3
Accessions EAW60841 EAW60842 EAW60843 EAW60844 EAW60845 Q9UH92 AA024982 AB209235 BAD92472 AF203978 AAF14638 AF213666 AAG40145 AF213667 AAG40146 AF213668 AAG40147 AK000150 BAA90977 AK290258 BAF82947 AK296114 BAG58863 AK303221 BAG64308 AK309628 AK314378 BAG37005 AK315432 BAG37820 BC010689 AAH10689 BC014537 BE907687 BI517590 BQ186038 BT009812 AAP88814 NM_170607 NP_733752 NM_198204 NP_937847 NM_198205 NP_937848
Function Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation. {ECO:0000269|PubMed:10593926, ECO:0000269|PubMed:12446771, ECO:0000269|PubMed:16782875}.
Subcellular Location Isoform Gamma: Nucleus. Note=Found predominantly in the nucleus.
Tissue Specificity Expressed in all tissues tested, including spleen, thymus, prostate, ovary, intestine, colon, peripheral blood leukocyte, heart, liver, skeletal muscle and kidney. Lower levels of expression in testis, brain, placenta and lung. {ECO:0000269|PubMed:10593926}.
Top Pathways Non-alcoholic fatty liver disease (NAFLD)

MAX-like protein X, ELISA Kit - MBS9337458 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 1.0 ng/ml
Range 3.12 ng/ml - 100 ng/ml

anti-MLX antibody - ARG65071 from Arigo Biolaboratories

Category ELISA Kit

Max-Like Protein X (MLX), ELISA Kit - MBS9396441 from MyBioSource

Category ELISA Kit

Max-Like Protein X (MLX), ELISA Kit - MBS9396449 from MyBioSource

Category ELISA Kit

Max-Like Protein X (MLX), ELISA Kit - MBS9396434 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Search more