MLX

Gene Symbol	MLX
Entrez Gene	6945
Alt Symbol	MAD7, MXD7, TCFL4, bHLHd13
Species	Human
Gene Type	protein-coding
Description	MLX, MAX dimerization protein
Other Description	BigMax protein|MAX-like bHLHZIP protein|class D basic helix-loop-helix protein 13|max-like protein X|transcription factor-like protein 4
Swissprots	Q9H2V1 Q53XM6 Q9H2V2 B2RD73 B2RAV8 Q9H2V0 Q96FL2 Q9NXN3 Q9UH92 A8K2J3
Accessions	EAW60841 EAW60842 EAW60843 EAW60844 EAW60845 Q9UH92 AA024982 AB209235 BAD92472 AF203978 AAF14638 AF213666 AAG40145 AF213667 AAG40146 AF213668 AAG40147 AK000150 BAA90977 AK290258 BAF82947 AK296114 BAG58863 AK303221 BAG64308 AK309628 AK314378 BAG37005 AK315432 BAG37820 BC010689 AAH10689 BC014537 BE907687 BI517590 BQ186038 BT009812 AAP88814 NM_170607 NP_733752 NM_198204 NP_937847 NM_198205 NP_937848
Function	Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation. {ECO:0000269|PubMed:10593926, ECO:0000269|PubMed:12446771, ECO:0000269|PubMed:16782875}.
Subcellular Location	Isoform Gamma: Nucleus. Note=Found predominantly in the nucleus.
Tissue Specificity	Expressed in all tissues tested, including spleen, thymus, prostate, ovary, intestine, colon, peripheral blood leukocyte, heart, liver, skeletal muscle and kidney. Lower levels of expression in testis, brain, placenta and lung. {ECO:0000269|PubMed:10593926}.
Top Pathways	Non-alcoholic fatty liver disease (NAFLD)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MLX full length protein - ab159654 from Abcam Category Protein Source Wheat germ Species Human

Human MLX protein fragment - ab116726 from Abcam Category Protein Source Wheat germ Species Human

MLX / TCFL4 Antibody Blocking Peptide - LS-E14526 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MLX / TCFL4 Antibody Blocking Peptide - LS-E14525 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MLX / TCFL4 Antibody Blocking Peptide - LS-E18515 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MLX / TCFL4 Antibody Blocking Peptide - LS-E27241 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MLX / TCFL4 Antibody Blocking Peptide - LS-E11806 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MLX / TCFL4 Antibody Blocking Peptide - LS-E11807 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MLX / TCFL4 Antibody Blocking Peptide - LS-E21343 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MLX / TCFL4 Antibody Blocking Peptide - LS-E9693 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MLX Partial Recombinant Protein - H00006945-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

MLX Recombinant Protein - H00006945-P02 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

MLX-Antibody-Center-Blocking-Peptide - BP8638c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MLX blocking peptide - GTX88235-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

TCFL4 Blocking Peptide - abx063335 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine

MLX Peptide - AC21-2063-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Max-like protein X - H00006945-P02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

Max-like protein X - H00006945-P02-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

Max-like protein X - H00006945-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Max-like protein X - H00006945-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MLX Peptide - 42-272P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

MLX fusion protein - ag2671 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

TCFL4 Blocking Peptide - CBP2141 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine

Mlx (Q136) Peptide - BS2160P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Max-like protein X(MLX) - CSB-YP014643HU CSB-EP014643HU CSB-BP014643HU CSB-MP014643HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

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