Gene Symbol | CCL23 |
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Entrez Gene | 6368 |
Alt Symbol | CK-BETA-8, CKb8, Ckb-8, Ckb-8-1, MIP-3, MIP3, MPIF-1, SCYA23, hmrp-2a |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-C motif) ligand 23 |
Other Description | C-C motif chemokine 23|C6 beta-chemokine|macrophage inflammatory protein 3|myeloid progenitor inhibitory factor 1|small inducible cytokine subfamily A (Cys-Cys), member 23 |
Swissprots | B7ZKQ3 P55773 Q52LD4 O75950 O00174 |
Accessions | AAC63326 AAC63327 EAW80103 EAW80104 P55773 BC093970 AAH93970 BC143310 AAI43311 BQ026575 U58913 AAD10846 U67128 AAD00161 U85767 AAB51134 XR_429910 XR_430786 NM_005064 NP_005055 NM_145898 NP_665905 |
Function | Shows chemotactic activity for monocytes, resting T- lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23. {ECO:0000269|PubMed:15905581}. |
Subcellular Location | Secreted. |
Tissue Specificity | High levels in adult lung, liver, skeletal muscle and pancreas. Moderate levels in fetal liver, adult bone marrow and placenta. The short form is the major species and the longer form was detected only in very low abundance. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are found in high levels in synovial fluids from rheumatoid patients. {ECO:0000269|PubMed:15905581}. |
Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |
MIP3 (CCL23) Human ELISA Kit - ab100611 from Abcam
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Human CCL23 / MIP3 ELISA Kit (Sandwich ELISA) - LS-F2899 from LifeSpan Bioscience
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Human CCL23 / MIP3 ELISA Kit (Sandwich ELISA) - LS-F5446 from LifeSpan Bioscience
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Human CCL23 / MIP3 ELISA Kit (Sandwich ELISA) - LS-F162 from LifeSpan Bioscience
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Human CCL23 / C-C Motif Chemokine 23 ELISA Kit - RAB0640 from Sigma-Aldrich
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Human MPIF-1 ELISA Kit - RAB0065 from Sigma-Aldrich
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Human CCL23/MPIF-1 DuoSet ELISA - DY131 from R&D Systems
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Human CCL23/Ck beta 8-1 DuoSet ELISA - DY508 from R&D Systems
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Human MPIF1 ELISA kit - 55R-1984 from Fitzgerald
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Human CCL23 ELISA Kit - orb219256 from Biorbyt
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Human CCL23 ELISA Kit - abx056042 from Abbexa
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Human MPIF-1 ELISA Kit - abx054581 from Abbexa
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C-C motif chemokine 23, CCL23, Human, ELISA Kit - E1574h from ARP American Research Products
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Myeloid Progenitor Inhibitory Factor 1, MPIF-1/CCL23, Human, ELISA Kit - E-EL-H1348 from ARP American Research Products
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Myeloid Progenitor Inhibitory Factor 1 (MPIF1), Human, ELISA Kit - SEB574Hu from ARP American Research Products
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Myeloid Progenitor Inhibitory Factor 1, Human, ELISA Kit - E01M0335 from ARP American Research Products
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Myeloid Progenitor Inhibitory Factor 1, MPIF-1, Human, ELISA Kit - CSB-E07309h from ARP American Research Products
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Macrophage Inflammatory Protein 3, MIP-3, Rat, ELISA Kit - E-EL-R0005 from ARP American Research Products
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Myeloid Progenitor Inhibitory Factor 1, MPIF-1/CCL23, Rabbit, ELISA Kit - E-EL-RB1088 from ARP American Research Products
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Myeloid Progenitor Inhibitory Factor 1, MPIF-1/CCL23, Chicken, ELISA Kit - E-EL-Ch0646 from ARP American Research Products
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Myeloid Progenitor Inhibitory Factor 1, MPIF-1/CCL23, Porcine, ELISA Kit - E-EL-P1522 from ARP American Research Products
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Myeloid Progenitor Inhibitory Factor 1, MPIF-1/CCL23, Monkey, ELISA Kit - E-EL-MK0941 from ARP American Research Products
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Myeloid Progenitor Inhibitory Factor 1 (MPIF1), Human, CLIA Kit - SCB574Hu from ARP American Research Products
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CCL23 (Human) IP-WB Antibody Pair - H00006368-PW2 from Acris Antibodies
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CCL23 (Human) ELISA Kit - KA1751 from Acris Antibodies
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